Evidence map›Paper›PMID 35795472›Full record

ReviewNeuro-oncology advances

Radiomics and radiogenomics in pediatric neuro-oncology: A review.

Rachel Madhogarhia, Debanjan Haldar, Sina Bagheri, Ariana Familiar, Hannah Anderson, Sherjeel Arif, Arastoo Vossough, Phillip Storm, Adam Resnick, Christos Davatzikos and 2 more

Abstract readReview
In one paragraph

Review in Neuro-oncology advances. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rachel MadhogarhiaDepartment of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Debanjan HaldarDepartment of Neurosurgery, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Sina BagheriCenter for Data-Driven Discovery in Biomedicine (D3b), Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Ariana FamiliarCenter for Data-Driven Discovery in Biomedicine (D3b), Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Hannah AndersonCenter for Data-Driven Discovery in Biomedicine (D3b), Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Sherjeel ArifCenter for Biomedical Image Computing and Analytics (CBICA), University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Arastoo VossoughCenter for Data-Driven Discovery in Biomedicine (D3b), Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Phillip StormDepartment of Neurosurgery, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Adam ResnickCenter for Data-Driven Discovery in Biomedicine (D3b), Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Christos DavatzikosCenter for Biomedical Image Computing and Analytics (CBICA), University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-1025-8561
Anahita Fathi KazerooniCenter for Biomedical Image Computing and Analytics (CBICA), University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Ali NabavizadehCenter for Data-Driven Discovery in Biomedicine (D3b), Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-0380-4552

Funding

User-ready tools and scalable workflows for INCLUDE datasets in the cloud: advancing brain imaging data management and analyticsU2CHL156291 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI Joaquin M. Espinosa · 2020 to 2026
$43.8M
NRSA Training CoreTL1TR001880 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI MEAGHER, EMMA ANNE · 2016 to 2025
$10.0M
Biomedical Image Computing and Informatics ClusterS10OD023495 · OD · UNIVERSITY OF PENNSYLVANIA · PI DAVATZIKOS, CHRISTOS · 2017 to 2017
$1.9M
NCATS NIH HHS TL1 TR001880NHLBI NIH HHS U2C HL156291NIH HHS S10 OD023495
6 · The paper itself

Abstract

The current era of advanced computing has allowed for the development and implementation of the field of radiomics. In pediatric neuro-oncology, radiomics has been applied in determination of tumor histology, identification of disseminated disease, prognostication, and molecular classification of tumors (ie, radiogenomics). The field also comes with many challenges, such as limitations in study sample sizes, class imbalance, generalizability of the methods, and data harmonization across imaging centers. The aim of this review paper is twofold: first, to summarize existing literature in radiomics of pediatric neuro-oncology; second, to distill the themes and challenges of the field and discuss future directions in both a clinical and technical context.

Indexed as

brain tumorsneuro-oncologypediatricsradiogenomicsradiomics

Identifiers

PMID35795472
PMCPMC9252112

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.