ReviewFrontiers in plant science2022
Intriguing Role of Proline in Redox Potential Conferring High Temperature Stress Tolerance.
Review in Frontiers in plant science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
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Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it, 101 citations in OpenAlex.
- Abiotic Stress in Crop Production.International journal of molecular sciences · 2023Pooled it
- The meiotic achilles' heel: vulnerability and resilience under environmental stress.Protoplasma · 2026Review
- Inoculation ofApplied and environmental microbiology · 2026Article
- Untargeted Metabolomics Reveals Metabolic Reprogramming During Viable but Non-Culturable State Formation inFoods (Basel, Switzerland) · 2026Article
- Transcriptome-Based WGCNA Reveals Hub Genes Involved in Copper Resistance ofInternational journal of molecular sciences · 2026Article
- Early physiological and biochemical modulation in garlic under drought and high temperature.Frontiers in plant science · 2026Article
- SbHsp70 overexpression enhances drought and salinity tolerance in wheat through improved cellular stability and stress-associated structural adaptations.Frontiers in plant science · 2026Article
- Fungal biotransformation of okara into functional food: Comparative species-dependent metabolomic and antioxidant profiles.Current research in food science · 2026Article
- Atelocollagen Increases Collagen Synthesis by Promoting Glycine Transporter 1 in Aged Mouse Skin.International journal of molecular sciences · 2025Article
- Meltome Atlas of Arabidopsis thaliana proteome: a melting temperature-based identification of heat and cold resistant proteins using in-silico approach.BMC genomics · 2025Article
- Anthocyanin biosynthesis enhances alkaline stress tolerance by upregulating antioxidant machinery and modulating ROS levels in three red landraces of rice.BMC plant biology · 2025Article
- Proline transporters balance the salicylic acid-mediated trade-off between regeneration and immunity in plants.bioRxiv : the preprint server for biology · 2025Article
- Activation of alternative oxidase ensures carbon supply for ethylene and carotenoid biosynthesis during tomato fruit ripening.Plant physiology · 2025Article
- Transcriptome profiling reveals key genes in eggplant (Solanum melongena) roots under salt stress.BMC genomics · 2025Article
- BPM Proteins Modulate Heat Stress Response inPlants (Basel, Switzerland) · 2025Article
- Integrated Metabolomic and Transcriptomic Analysis Reveals the Molecular Regulatory Mechanism of Gamma-Aminobutyric Acid Accumulation in White Quinoa (Foods (Basel, Switzerland) · 2025Article
- Spermidine-induced improvements in water relations and antioxidant defense enhance drought tolerance in yarrow (Heliyon · 2025Article
- Proline Promotes Drought Tolerance in Maize.Biology · 2025Article
- Exploring regulatory roles of putrescine-doped zinc oxide nanoentities on ethylene signaling, redox imbalance, and programmed cell death in drought-stressed rice (Frontiers in plant science · 2025Article
- Identifying candidate genes for sugar accumulation in sugarcane: an integrative approach.BMC genomics · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Proline is a proteinogenic amino acid synthesized from glutamate and ornithine. Pyrroline-5-carboxylate synthetase and pyrroline-5-carboxylate reductase are the two key enzymes involved in proline synthesis from glutamate. On the other hand, ornithine-δ-aminotransferase converts ornithine to pyrroline 5-carboxylate (P5C), an intermediate in the synthesis of proline as well as glutamate. Both proline dehydrogenase and P5C dehydrogenase convert proline back to glutamate. Proline accumulation is widespread in response to environmental challenges such as high temperatures, and it is known to defend plants against unpropitious situations promoting plant growth and flowering. While proline accumulation is positively correlated with heat stress tolerance in some crops, it has detrimental consequences in others. Although it has been established that proline is a key osmolyte, its exact physiological function during heat stress and plant ontogeny remains unknown. Emerging evidence pointed out its role as an overriding molecule in alleviating high temperature stress (HTS) by quenching singlet oxygen and superoxide radicals. Proline cycle acts as a shuttle and the redox couple (NAD
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.