Evidence map›Paper›PMID 35794997›Full record

ArticleOpen medicine (Warsaw, Poland)2022

β2-Adrenergic receptor expression in subchondral bone of patients with varus knee osteoarthritis.

Xiaochun Yang, Xuegang Liang, Haohui Guo, Long Ma, Li Jian, Xin Zhao, Jian Wang, Lvlin Yang, Zhiqiang Meng, Qunhua Jin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open medicine (Warsaw, Poland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Xiaochun YangDepartment of Orthopedics Ward 3, The General Hospital of Ningxia Medical University, Yinchuan, 750004, Ningxia, China.
Xuegang LiangDepartment of The General Hospital of Ningxia Medical University, Ningxia Medical University, Yinchuan, 750004, Ningxia, China.
Haohui GuoDepartment of Orthopedics Ward 3, The General Hospital of Ningxia Medical University, Yinchuan, 750004, Ningxia, China.
Long MaDepartment of Orthopedics Ward 3, The General Hospital of Ningxia Medical University, Yinchuan, 750004, Ningxia, China.
Li JianDepartment of Pathology, The General Hospital of Ningxia Medical University, Yinchuan, 750004, Ningxia, China.
Xin ZhaoDepartment of Orthopedics Ward 3, The General Hospital of Ningxia Medical University, Yinchuan, 750004, Ningxia, China.
Jian WangDepartment of Orthopedics Ward 3, The General Hospital of Ningxia Medical University, Yinchuan, 750004, Ningxia, China.
Lvlin YangDepartment of The General Hospital of Ningxia Medical University, Ningxia Medical University, Yinchuan, 750004, Ningxia, China.
Zhiqiang MengDepartment of The General Hospital of Ningxia Medical University, Ningxia Medical University, Yinchuan, 750004, Ningxia, China.
Qunhua JinDepartment of Orthopedics Ward 3, The General Hospital of Ningxia Medical University, Yinchuan, 750004, Ningxia, China.
Ningxia Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An important causative factor in osteoarthritis (OA) is the abnormal mechanical stress-induced bone remodeling of the subchondral bone. β2-adrenergic receptor (Adrb2) plays a major role in mechanical stresses that induce bone remodeling. The medial tibial plateau (MTP) and lateral tibial plateau (LTP) of patients with varus Knee osteoarthritis (KO) bear different mechanical stresses. The present study aimed to investigate the expression of Adrb2 in medial tibial plateau subchondral bone (MTPSB) and lateral tibial plateau subchondral bone (LTPSB) in patients with varus KO. A total of 30 tibial plateau samples from patients undergoing total knee arthroplasty for varus KO and MTPSB and LTPSB were studied. Statistical analysis was performed using paired sample

Indexed as

bone remodelingmechanical stressesosteoarthritissubchondral boneβ2-adrenergic receptor

Identifiers

PMID35794997
PMCPMC9175016
OpenAlexW4285070250

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.