Evidence map›Paper›PMID 35794986›Full record

ArticleJournal of oncology2022

Construction of a Prognostic Immune-Related LncRNA Risk Model for Gastric Cancer.

Wei Ding, Pengcheng Sun, Yulin Tan, Huaji Jiang, Cheng Xi, Ling Zhuang, Yixin Xu, Xuezhong Xu

Abstract read
In one paragraph

Article in Journal of oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wei DingDepartment of General Surgery, Wujin Hospital Affiliated to Jiangsu University, Changzhou 213017, China.ORCID https://orcid.org/0000-0001-6990-8621
Pengcheng SunDepartment of Oncology, The Third Affiliated Hospital of Soochow University, Changzhou 213001, China.ORCID https://orcid.org/0000-0003-2764-8555
Yulin TanDepartment of General Surgery, Wujin Hospital Affiliated to Jiangsu University, Changzhou 213017, China.
Huaji JiangDepartment of General Surgery, Wujin Hospital Affiliated to Jiangsu University, Changzhou 213017, China.
Cheng XiDepartment of General Surgery, Wujin Hospital Affiliated to Jiangsu University, Changzhou 213017, China.
Ling ZhuangDepartment of General Surgery, Wujin Hospital Affiliated to Jiangsu University, Changzhou 213017, China.
Yixin XuDepartment of General Surgery, Wujin Hospital Affiliated to Jiangsu University, Changzhou 213017, China.
Xuezhong XuDepartment of General Surgery, Wujin Hospital Affiliated to Jiangsu University, Changzhou 213017, China.ORCID https://orcid.org/0000-0001-9232-3381

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer (GC) is one of the most common malignancies, and novel prognostic biomarkers for it are urgently required. This study is aimed at screening a group of immune-related lncRNAs (IRLs) in predicting the prognosis of GC patients. Genetic and clinical information from the 360 GC patients was included in this study. Eight IRLs in lncRNA-miRNA-mRNA network were screened out according to differential expression analysis. A novel risk score model with three IRLs (MIR4435-1HG, UCA1, and RP11-617F23.1) were identified, and patients were assigned to a high-risk group and a low-risk group. Patients in the low-risk group had a better prognosis. In addition, two nomograms were developed to predict the prognosis of GC. We evaluated the correlation between IRLs and the immune infiltration level of GC using TIMER. Furthermore, we verified that RP11-617F23.1 was significantly upregulated in human GC tissues compared with their adjacent tissues. And, patients with high RP11-617F23.1 expression in tumor tissues had poorer survival. In conclusion, we established a novel risk model based on IRLs for predicting the prognosis of GC. Meanwhile, a novel IRL, RP11-617F23.1, could serve as a predictor of prognosis for patients with GC.

Identifiers

PMID35794986
PMCPMC9252720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.