Evidence map›Paper›PMID 35794929›Full record

ArticleOpen forum infectious diseases2022

Prior Pulmonary Tuberculosis Is a Risk Factor for Asymptomatic Cryptococcal Antigenemia in a Cohort of Adults With Advanced Human Immunodeficiency Virus Disease.

Rachel M Wake, Nazir A Ismail, Shaheed V Omar, Farzana Ismail, Caroline T Tiemessen, Thomas S Harrison, Joseph N Jarvis, Nelesh P Govender

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Association of Antibody Immunity With Cryptococcal Antigenemia and Mortality in a South African Cohort With Advanced Human Immunodeficiency Virus Disease.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rachel M WakeInstitute for Infection and Immunity, St George's University Hospital NHS Foundation Trust, London, United Kingdom.ORCID https://orcid.org/0000-0003-3193-4888
Nazir A IsmailFaculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Shaheed V OmarFaculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Farzana IsmailDepartment of Medical Microbiology, University of Pretoria, Pretoria, South Africa.
Caroline T TiemessenFaculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Thomas S HarrisonInstitute for Infection and Immunity, St George's University Hospital NHS Foundation Trust, London, United Kingdom.
Joseph N JarvisDepartment of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Nelesh P GovenderInstitute for Infection and Immunity, St George's University Hospital NHS Foundation Trust, London, United Kingdom.

Funding

Phased Implementation of a Public Health Programme: Cryptococcal Screening and Treatment in South AfricaR01AI118511 · NIAID · UNIVERSITY OF MINNESOTA · PI BOULWARE, DAVID R, GOVENDER, NELESH PREMAPRAGASAN · 2016 to 2020
$2.9M
Medical Research Council MR/V033417/1NIAID NIH HHS R01 AI118511
6 · The paper itself

Abstract

The greater mortality risk among people with advanced human immunodeficiency virus disease and cryptococcal antigenemia, despite treatment, indicates an increased susceptibility to other infections. We found that prior tuberculosis was an independent risk factor for cryptococcal antigenemia (adjusted odds ratio, 2.72; 95% confidence interval, 1.13-6.52;

Indexed as

advanced HIV diseasecryptococcosistuberculosis

Identifiers

PMID35794929
PMCPMC9251663

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.