Evidence map›Paper›PMID 35794885›Full record

ArticleInternational journal of surgery protocols2022

Topical Treatments in Reducing

Yash Sewpaul, Brook Leung, Alexander W Hartland, Sandeep Krishan Nayar, Mustafa S Rashid

Open access · diamondAbstract read
In one paragraph

Article in International journal of surgery protocols, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Topical Treatments in ReducingInternational journal of surgery protocols · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Yash SewpaulLancaster Medical School, Lancaster University, LA1 4YW, GB.ORCID https://orcid.org/0000-0001-9567-7353
Brook LeungRoyal London Hospital, Whitechapel Rd, London, E1 1FR, UK.ORCID https://orcid.org/0000-0002-5297-8014
Alexander W HartlandNorthampton General Hospital, Cliftonville, Northampton, NN1 5BD, UK.ORCID https://orcid.org/0000-0001-8423-2324
Sandeep Krishan NayarRoyal London Hospital, Whitechapel Rd, London, E1 1FR, UK.ORCID https://orcid.org/0000-0003-2202-580X
Mustafa S RashidNuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, Windmill Road, Oxford, OX3 7LD, UK.ORCID https://orcid.org/0000-0002-6236-4120
Royal London Hospital · GBLancaster University · GBNorthampton General Hospital · GBNuffield Orthopaedic Centre · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Methods: The study protocol was designed and registered prospectively on PROSPERO (International prospective register for systematic reviews). Databases used for the literature search will include MEDLINE, EMBASE, PsycINFO, and The Cochrane Library. Randomised controlled trials (RCTs) evaluating the use of any topical preparation against placebo, in all types of shoulder surgery, will be included. Our primary outcome is the number of colony forming units of P acnes. Secondary outcomes will include adverse events such as skin irritation, wound dehiscence, and the incidence of revision surgery due to infection. The Cochrane Risk of Bias Tool 2.0 and Jadad score will be used to assess the quality of methodology of the studies. Statistical analysis will be used to assess inconsistency and bias across included studies. Comparable outcome data will be pooled and analysed quantitatively or qualitatively as appropriate. Ethics and dissemination: No ethical clearances required for this study. This systematic review and meta-analysis will be published in a peer-reviewed journal. Highlights: Various topical strategies have been investigated to reduce the prevalence of P acnes, the most common identifiable cause of periprosthetic shoulder joint infection, with several demonstrating efficacy in reducing the positive culture.This systematic review and meta-analysis evaluates the effectiveness of topical preparations in reducing the prevalence of P acnes in shoulder surgery.Our primary outcome is the number of colony forming units of P acnes. Registration: PROSPERO 2022 CRD42022310312.

Indexed as

CultureInfectionPropionibacterium acnesShoulder surgeryTopical preparations

Identifiers

PMID35794885
PMCPMC9187290
OpenAlexW4285208917

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.