Evidence map›Paper›PMID 35794856›Full record

ArticleOrthopaedic surgery2022

Bone Cement and Pedicle Screw for the Treatment of Spinal Tumors with Spinal Cord Compression and Posterior Wall Defects.

Xiaofeng Shao, Jian Wu, Zhangzhe Zhou, Nanning Lv, Kangwu Chen, Shuangjun He, Zhiyong Sun, Zhonglai Qian

Open access · goldAbstract read
In one paragraph

Article in Orthopaedic surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. A three-dimensional finite element-based biomechanical properties analysis of the 10th thoracic vertebra invaded by bone metastases for clinical procedure optimization.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Xiaofeng ShaoThe Department of Orthopaedic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, China.
Jian WuThe Department of Orthopaedic Surgery, Changsu No.2. People's Hospital, Suzhou, China.
Zhangzhe ZhouThe Department of Orthopaedic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, China.
Nanning LvDepartment of Orthopaedic Surgery, The Second People's Hospital of Lianyungang, Lianyungang, China.
Kangwu ChenThe Department of Orthopaedic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, China.
Shuangjun HeDepartment of Orthopaedic Surgery, Affiliated Danyang Hospital of Nantong University, Danyang, China.
Zhiyong SunThe Department of Orthopaedic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, China.
Zhonglai QianThe Department of Orthopaedic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, China.ORCID https://orcid.org/0000-0002-0737-9696
Soochow University · CNChangzhou No.2 People's Hospital · CNNantong University · CNThe First People’s Hospital of Lianyungang · CN

Funding

Soochow University
6 · The paper itself

Abstract

objectiveTo compare the safety and efficacy of posterior internal fixation with open vertebroplasty (VP) and posterior internal fixation with open kyphoplasty (KP) in the treatment of metastatic epidural spinal cord compression (MESCC) with posterior wall destruction.

methodsThis retrospective study, conducted between January 2016 and May 2019, equally divided 60 patients with MESCC and posterior wall destruction into two groups based on the surgical method: open vertebroplasty with pedicle screw fixation (VP group) and open kyphoplasty with pedicle screw fixation (KP group). Visual analogue scale (VAS), SF-36 scores, middle vertebral height (MVH), and posterior vertebral height (PVH) were evaluated for the two groups preoperatively, postoperatively, and 1 year after surgery. Spinal Instability Neoplastic Score, Frankel grades and complications were recorded and evaluated.

resultsFive patients were excluded from the analysis, and our study cohort consisted of 55 adult patients who met the inclusion criteria. The VAS and SF-36 scores of these two groups of patients significantly improved, when compared with those before the surgery (P < 0.05). There were significant differences in total cost (8835 ± 1468 vs 9540 ± 053 USD) and cement volume (4.51 ± 0.96 ml vs 6.35 ± 1.09 ml) between two groups (P < 0.05). The MVH and PVH of these two groups of patients significantly improved, when compared with those before the surgery (P < 0.05). The MVH was significantly larger in the KP group than in the VP group postoperatively (20.15 ± 4.86 vs 17.70 ± 3.78, P < 0.05) and at the final follow-up (20.42 ± 5.59 vs 17.28 ± 3.23, P < 0.05). However, the PVH of the two groups did not significantly differ at the two postoperative follow-ups (P > 0.05). No significant differences were found in surgery time, time from surgery to discharge, blood loss and complications between both groups postoperatively (P > 0.05).

conclusionIn the short term, both approaches are effective and safe in patients with MESCC and posterior wall destruction. The posterior internal fixation with open VP may be a good choice of surgical method in patients with MESCC and posterior wall defects.

Indexed as

Fractures, CompressionPedicle ScrewsSpinal Cord CompressionSpinal Cord NeoplasmsSpinal FracturesSpinal NeoplasmsVertebroplastyAdultBone CementsHumansLumbar VertebraeRetrospective StudiesTreatment OutcomeBone CementsKyphoplastyMetastatic spinal tumorsPedicle screw fixationSpinal cord compressionVertebroplasty

Identifiers

PMID35794856
PMCPMC9363719
OpenAlexW4284889860

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.