Evidence map›Paper›PMID 35794769›Full record

ReviewCurrent neuropharmacology2023

Epilepsy in Cerebrovascular Diseases: A Narrative Review.

Sabrina Neri, Sara Gasparini, Angelo Pascarella, Domenico Santangelo, Vittoria Cianci, Anna Mammì, Michele Lo Giudice, Edoardo Ferlazzo, Umberto Aguglia

Open access · greenAbstract readReview
In one paragraph

Review in Current neuropharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Sabrina NeriDepartment of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.
Sara GaspariniDepartment of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.
Angelo PascarellaDepartment of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.
Domenico SantangeloDepartment of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.
Vittoria CianciRegional Epilepsy Centre, Great Metropolitan Hospital, Reggio Calabria, Italy.
Anna MammìDepartment of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.
Michele Lo GiudiceDepartment of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.
Edoardo FerlazzoDepartment of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.
Umberto AgugliaDepartment of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.
Magna Graecia University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEpilepsy is a common comorbidity of cerebrovascular disease and an increasing socioeconomic burden.

objectiveWe aimed to provide an updated comprehensive review on the state of the art about seizures and epilepsy in stroke, cerebral haemorrhage, and leukoaraiosis.

methodsWe selected English-written articles on epilepsy, stroke, and small vessel disease up until December 2021. We reported the most recent data about epidemiology, pathophysiology, prognosis, and management for each disease.

resultsThe main predictors for both ES and PSE are the severity and extent of stroke, the presence of cortical involvement and hemorrhagic transformation, while PSE is also predicted by younger age at stroke onset. Few data exist on physiopathology and seizure semiology, and no randomized controlled trial has been performed to standardize the therapeutic approach to post-stroke epilepsy.

conclusionSome aspects of ES and PSE have been well explored, particularly epidemiology and risk factors. On the contrary, few data exist on physiopathology, and existing evidence is mainly based on studies on animal models. Little is also known about seizure semiology, which may also be difficult to interpret by non-epileptologists. Moreover, the therapeutic approach needs standardization as regards indications and the choice of specific ASMs. Future research may help to better elucidate these aspects.

Indexed as

Cerebrovascular DisordersEpilepsyStrokeAnimalsComorbiditySeizurescerebral haemorrhagecerebrovascular diseaseepilepsyleukoaraiosispost-stroke epilepsySeizuresstroke

Identifiers

PMID35794769
PMCPMC10514540
OpenAlexW4284708928

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.