Evidence map›Paper›PMID 35794604›Full record

ArticleEnvironmental health : a global access science source2022

Birch pollen, air pollution and their interactive effects on airway symptoms and peak expiratory flow in allergic asthma during pollen season - a panel study in Northern and Southern Sweden.

Hanne Krage Carlsen, Susanna Lohman Haga, David Olsson, Annelie F Behndig, Lars Modig, Kadri Meister, Bertil Forsberg, Anna-Carin Olin

Open access · goldAbstract read
In one paragraph

Article in Environmental health : a global access science source, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 31 citations in OpenAlex.

  1. Trial
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  6. Genetic mechanisms of pollinosis: interactions between genes and environmental factors.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Review
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  8. Article
  9. Article
  10. [Study on allergen components of birch pollen in Beijing area].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2024
    Article
  11. Article
  12. The Effects of Wildfire Smoke on Asthma and Allergy.Current allergy and asthma reports · 2023
    Review
  13. The Concept of One Health for Allergic Diseases and Asthma.Allergy, asthma & immunology research · 2023
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Hanne Krage CarlsenSection of Occupational and Environmental Medicine, School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Medicinaregatan 16A, 40530, Gothenburg, Sweden. hanne.krage.carlsen@amm.gu.se.ORCID 0000-0003-1656-9624
Susanna Lohman HagaSection of Occupational and Environmental Medicine, School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Medicinaregatan 16A, 40530, Gothenburg, Sweden.
David OlssonDepartment of Public Health and Clinical Medicine, University Hospital, Sustainable Health, Umeå University, Building 1A, 4st, 901 87, Umeå, Sweden.
Annelie F BehndigSection of Medicine, Department of Public Health and Clinical Medicine, University Hospital, Umeå University, Building 1A, 4st, 901 87, Umeå, Sweden.
Lars ModigDepartment of Public Health and Clinical Medicine, University Hospital, Sustainable Health, Umeå University, Building 1A, 4st, 901 87, Umeå, Sweden.
Kadri MeisterDepartment of Statistics, USBE, Social Sciences Building Level 2 (ground floor), Umeå University, 90187, Umeå, Sweden.
Bertil ForsbergDepartment of Public Health and Clinical Medicine, University Hospital, Sustainable Health, Umeå University, Building 1A, 4st, 901 87, Umeå, Sweden.
Anna-Carin OlinSection of Occupational and Environmental Medicine, School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Medicinaregatan 16A, 40530, Gothenburg, Sweden.
Umeå University · SEUniversity of Gothenburg · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEvidence of the role of interactions between air pollution and pollen exposure in subjects with allergic asthma is limited and need further exploration to promote adequate preventive measures. The objective of this study was to assess effects of exposure to ambient air pollution and birch pollen on exacerbation of respiratory symptoms in subjects with asthma and allergy to birch.

methodsThirty-seven subjects from two Swedish cities (Gothenburg and Umeå) with large variation in exposure to both birch-pollen and air pollutants, participated in the study. All subjects had confirmed allergy to birch and self-reported physician-diagnosed asthma. The subjects recorded respiratory symptoms such as rhinitis or eye irritation, dry cough, dyspnoea, the use of any asthma or allergy medication and peak respiratory flow (PEF), daily for five consecutive weeks during two separate pollen seasons and a control season without pollen. Nitrogen oxides (NO

resultsDuring pollen seasons all symptoms and medication use were higher, and PEF was reduced in the subjects. In regression analysis, exposure to pollen at lags 0 to 2 days, and lags 0 to 6 days was associated with increased ORs of symptoms and decreased RRs for PEF. Pollen and air pollution interacted in some cases; during low pollen exposure, there were no associations between air pollution and symptoms, but during high pollen exposure, O

conclusionsPollen and air pollutants interacted to increase the effect of air pollution on respiratory symptoms in allergic asthma. Implementing the results from this study, advisories for individuals with allergic asthma could be improved, minimizing the morbidities associated with the condition.

Indexed as

Air PollutantsAir PollutionAsthmaHypersensitivityRhinitisRhinitis, Allergic, SeasonalBetulaHumansParticulate MatterPollenSeasonsSwedenAir PollutantsParticulate MatterAllergic asthmaBetulaBirchO3Panel studyPM2.5Pollen season

Identifiers

PMID35794604
PMCPMC9258213
OpenAlexW4283838108

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.