Evidence map›Paper›PMID 35794454›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2022

Freeform 3D Ice Printing (3D-ICE) at the Micro Scale.

Akash Garg, Saigopalakrishna S Yerneni, Phil Campbell, Philip R LeDuc, O Burak Ozdoganlar

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Three-dimensional printing of ice structures via evaporative cooling in vacuum.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Article
  5. Ice-phase optothermal tweezers.Nature communications · 2026
    Article
  6. Review
  7. Review
  8. Physics of microscale freeform 3D printing of ice.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Cryo-Electrohydrodynamic Jetting of Aqueous Silk Fibroin Solutions.ACS biomaterials science & engineering · 2024
    Article
  10. Review
  11. Freeform 3D Ice Printing (3D-ICE) at the Micro Scale.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Akash GargDepartment of Mechanical Engineering, Carnegie Mellon University, Pittsburgh, PA, 15232, USA.
Saigopalakrishna S YerneniDepartment of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA, 15232, USA.
Phil CampbellDepartment of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA, 15232, USA.
Philip R LeDucDepartments of Mechanical Engineering, Biomedical Engineering, Biological Sciences and Computational Biology, Carnegie Mellon University, Pittsburgh, PA, 15232, USA.
O Burak OzdoganlarDepartments of Mechanical Engineering, Biomedical Engineering and Material Science and Engineering, Carnegie Mellon University, Pittsburgh, PA, 15232, USA.ORCID 0000-0001-5098-5184

Funding

3D Freeform Ice Printing to Create Tissues with Biomimetic VasculatureR21AR081052 · NIAMS · CARNEGIE-MELLON UNIVERSITY · PI OZDOGANLAR, BURAK O. · 2022 to 2023
$313k
Carnegie Mellon University Bioengineered Organs InitiativeDowd Fellowship N/ANIAMS NIH HHS R21 AR081052
6 · The paper itself

Abstract

Water is one of the most important elements for life on earth. Water's rapid phase-change ability along with its environmental and biological compatibility also makes it a unique structural material for 3D printing of ice structures reproducibly and accurately. This work introduces the freeform 3D ice printing (3D-ICE) process for high-speed and reproducible fabrication of ice structures with micro-scale resolution. Drop-on-demand deposition of water onto a -35 °C platform rapidly transforms water into ice. The dimension and geometry of the structures are critically controlled by droplet ejection frequency modulation and stage motions. The freeform approach obviates layer-by-layer construction and support structures, even for overhang geometries. Complex and overhang geometries, branched hierarchical structures with smooth transitions, circular cross-sections, smooth surfaces, and micro-scale features (as small as 50 µm) are demonstrated. As a sample application, the ice templates are used as sacrificial geometries to produce resin parts with well-defined internal features. This approach could bring exciting opportunities for microfluidics, biomedical devices, soft electronics, and art.

Indexed as

MicrofluidicsPrinting, Three-DimensionalWaterWatercryogenic printingfree-form printinghierarchical channelsice printingice templatingmicro-castingout-of-plane printing

Identifiers

PMID35794454
PMCPMC9507341

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.