Evidence map›Paper›PMID 35794311›Full record

ArticleInflammation2022

Null Function of Npr1 Disturbs Immune Response in Colonic Inflammation During Early Postnatal Stage.

Changkun Long, Hongfei Liu, Wenxing Zhan, Liping Chen, Andong Wu, Lin Yang, Shenghan Chen

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Inflammation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Changkun LongVascular Function Laboratory, Human Aging Research Institute and School of Life Science, and Jiangxi Key Laboratory of Human Aging, Nanchang University, Nanchang, 330031, China.
Hongfei LiuVascular Function Laboratory, Human Aging Research Institute and School of Life Science, and Jiangxi Key Laboratory of Human Aging, Nanchang University, Nanchang, 330031, China.
Wenxing ZhanVascular Function Laboratory, Human Aging Research Institute and School of Life Science, and Jiangxi Key Laboratory of Human Aging, Nanchang University, Nanchang, 330031, China.
Liping ChenVascular Function Laboratory, Human Aging Research Institute and School of Life Science, and Jiangxi Key Laboratory of Human Aging, Nanchang University, Nanchang, 330031, China.
Andong WuAging and Vascular DiseasesSchool of Life Scienceand Jiangxi Key Laboratory of Human Aging, Human Aging Research Institute, Nanchang University, Nanchang, 330031, China.
Lin YangDepartment of Nephrology, Jiangxi Provincial People's Hospital, Affiliated to Nanchang University, Nanchang, 330006, China.
Shenghan ChenVascular Function Laboratory, Human Aging Research Institute and School of Life Science, and Jiangxi Key Laboratory of Human Aging, Nanchang University, Nanchang, 330031, China. chenshenghan@ncu.edu.cn.ORCID http://orcid.org/0000-0002-6521-7791
Nanchang University · CN

Funding

Key Programs of the Jiangxi Province, China. 20181BCD40001Key Research and Development Program of Hunan Province of China 2020YFC2002900National Natural Science Foundation of China 81771514National Natural Science Foundation of China 82071592
6 · The paper itself

Abstract

Natriuretic peptide receptor 1 (NPR1) is conventionally known as a regulator of vascular homeostasis. Here, we generated an Npr1 knockout mouse model with CRISPR/Cas9 technology and found that homozygous mice (Npr1

Indexed as

ColitisAnimalsCyclic GMPDextran SulfateDisease Models, AnimalImmunityInflammationMiceMice, Inbred C57BLMice, KnockoutThionucleotides8-bromoguanosino-3',5'-cyclic monophosphorothioateCyclic GMPDextran SulfateThionucleotidesCD4+ T cellscolitiscolonic inflammationimmune responseNpr1

Identifiers

PMID35794311
PMCPMC9646613
OpenAlexW4284889588

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.