ArticleScientific reports2022
Clinical pharmacist interventions in ambulatory psychogeriatric patients with excessive polypharmacy.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Evaluating the impact of pharmacists in outpatient mental health settings: a systematic review.International journal of clinical pharmacy · 2026Pooled it
- Effectiveness of a hierarchical pharmacist management model on reducing hyperphosphatemia in hemodialysis patients in China: a multicenter randomized study.Scientific reports · 2026Trial
- Article
- Impact of clinical pharmacist interventions on drug-related problems in hospitalised patients with renal dysfunction: a quasi-experimental study.Scientific reports · 2026Article
- Medication review in older adults at hospital discharge: an analysis of data from the IATROPREV study.European geriatric medicine · 2026Observational
- Article
- Attitudes and confidence toward deprescribing: a survey among Italian general practitioners.BMC primary care · 2025Observational
- Pharmacist prescriber implementation in the experiences of general practitioners, pharmacist prescribers and patients: qualitative study based on pilot trial in Slovenia.Frontiers in pharmacology · 2025Article
- Clinical pharmacist interventions in medication review for medication optimization in older hospitalized adults with mental disorders and somatic comorbidities: evidence from retrospective study.Frontiers in pharmacology · 2025Article
- Complex Psychotropic Polypharmacy in Soweto-based community psychiatry clinics.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2025Article
- Assessment of Potential Drug-Drug Interactions of Psycholeptics and Antidepressants in Outpatient Settings.Pharmacy (Basel, Switzerland) · 2024Article
- Psychodynamic Insights into Treatment-Resistant Pharmacotherapy: A Case Study Exploring Patient-Physician Dynamics and Adherence to Evidence-Based Practices.Journal of personalized medicine · 2024Article
- The Impact of Pharmacist Medication Reviews on Geriatric Patients: A Scoping Review.Korean journal of family medicine · 2024Article
- Characteristics of clinical-pharmacological recommendations in psychiatry in Germany.International journal of psychiatry in medicine · 2024Article
- Discrepancies in Electronic Medical Prescriptions Found in a Hospital Emergency Department: A Prospective Observational Study.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Clinical pharmacist recommendations in daily interdisciplinary ward rounds at a psychiatric hospital: a retrospective pre-post study on drug-related problems focused in somatic comorbidities.Frontiers in psychiatry · 2024Article
- Article
- Association between benzodiazepine anxiolytic polypharmacy and concomitant psychotropic medications in Japan: a retrospective cross-sectional study.Frontiers in psychiatry · 2024Article
- Case report: Time response of plasma clozapine concentrations on cessation of heavy smoking.Frontiers in pharmacology · 2024Article
- Attitudes and psychotropic preferences of primary care providers in the management of mental disorders: a web-based survey.Frontiers in medicine · 2024Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Psychogeriatric primary care patients are frequently treated with excessive polypharmacy (≥ 10 medications), leading to complications and increased costs. Such cases are rarely included in treatment guidelines and randomized controlled trials. This paper evaluates the impact of clinical pharmacist medication reviews on the quality of pharmacotherapy in primary care psychogeriatric patients with excessive polypharmacy. The retrospective observational multicentric pre-post study included patients (aged 65 or above) treated with at least one psychotropic and ten or more medications. Clinical pharmacists' recommendations were retrieved from medication review forms for the period 2012-2014. The study outcome measures were the number of medications, potentially inappropriate medications in the elderly (PIMs), potential drug-drug interactions which should be avoided (pXDDIs), and adherence to treatment guidelines. The study included 246 patients receiving 3294 medications, of which 14.6% were psychotropics. The clinical pharmacists proposed 374 interventions in psychopharmacotherapy. The general practitioners accepted 45.2% of them (169). Accepting clinical pharmacist recommendations reduced the total number of medications by 7.5% from 13.4 to 12.4 per patient (p < 0.05), the total number of prescribed PIMs by 21.8% from 312 to 244 (p < 0.05), the number of pXDDIs by 54.9% from 71 to 31 (p < 0.05) and also improved treatment guidelines adherence for antidepressants and antipsychotics (p < 0.05). Clinical pharmacist interventions significantly improved the quality of psychopharmacotherapy by reducing the total number of medications, PIMs, and pXDDIs. Accepting clinical pharmacist interventions led to better treatment guidelines adherence.
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