Evidence map›Paper›PMID 35794134›Full record

ArticleScientific reports2022

Overcoming addition of phosphoethanolamine to lipid A mediated colistin resistance in Acinetobacter baumannii clinical isolates with colistin-sulbactam combination therapy.

Sukrit Srisakul, Dhammika Leshan Wannigama, Paul G Higgins, Cameron Hurst, Shuichi Abe, Parichart Hongsing, Thammakorn Saethang, Sirirat Luk-In, Tingting Liao, Naris Kueakulpattana and 9 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
2.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Molecular Characterization of Colistin-Resistant ClinicalAntibiotics (Basel, Switzerland) · 2026
    Article
  5. Review
  6. Review
  7. Article
  8. Eravacycline Treatment for Carbapenem-ResistantInfection and drug resistance · 2025
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Polymyxins: recent advances and challenges.Frontiers in pharmacology · 2024
    Review
  19. Characterization of aFrontiers in cellular and infection microbiology · 2024
    Article
  20. Prognostic Factors That Affect Mortality Patients withInfection and drug resistance · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 12 institutions in 8 countries.

Sukrit Srisakul *Department of Microbiology, Faculty of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, 1873 Rama 4 Road, Pathum Wan, Bangkok, 10330, Thailand.
Dhammika Leshan WannigamaDepartment of Microbiology, Faculty of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, 1873 Rama 4 Road, Pathum Wan, Bangkok, 10330, Thailand.
Paul G Higgins *Institute for Medical Microbiology, Immunology and Hygiene, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Cameron Hurst *Statistics, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.
Shuichi AbeDepartment of Infectious Diseases and Infection Control, Yamagata Prefectural Central Hospital, Yamagata, Japan.
Parichart Hongsing *Department of Brain and Neurology, Mae Fah Luang University Hospital, Chiang Rai, Thailand.
Thammakorn SaethangDepartment of Computer Science, Faculty of Science, Kasetsart University, Bangkok, Thailand.
Sirirat Luk-In *Department of Clinical Microbiology and Applied Technology, Faculty of Medical Technology, Mahidol University, Bangkok, Thailand.
Tingting LiaoDepartment of Physiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Naris KueakulpattanaDepartment of Microbiology, Faculty of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, 1873 Rama 4 Road, Pathum Wan, Bangkok, 10330, Thailand.
Aye Mya Sithu SheinDepartment of Microbiology, Faculty of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, 1873 Rama 4 Road, Pathum Wan, Bangkok, 10330, Thailand.
Lin GanDepartment of General Surgery, Fuling Center Hospital of Chongqing City, Chongqing, China.
Rosalyn KupwiwatChulabhorn International College of Medicine, Thammasat University, Bangkok, Thailand.
Chanikan TanasatitchaiDepartment of Microbiology, Faculty of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, 1873 Rama 4 Road, Pathum Wan, Bangkok, 10330, Thailand.
Pattama WapeesittipanDepartment of Clinical Science, University of Bergen, Bergen, Norway.
Phatthranit PhattharapornjaroenDepartment of Emergency Medicine, Center of Excellence, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Vishnu Nayak BadavathSchool of Pharmacy & Technology Management,, SVKM's Narsee Monjee Institute of Management Studies (NMIMS), Hyderabad, 509301, India.
Asada LeelahavanichkulDepartment of Microbiology, Faculty of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, 1873 Rama 4 Road, Pathum Wan, Bangkok, 10330, Thailand.
Tanittha ChatsuwanDepartment of Microbiology, Faculty of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, 1873 Rama 4 Road, Pathum Wan, Bangkok, 10330, Thailand. Tanittha.C@chula.ac.th.
Chulalongkorn University · THMahidol University · THThai Red Cross Society · THFuling Center Hospital of Chongqing · CNKasetsart University · THMae Fah Luang University Hospital · THNarsee Monjee Institute of Management Studies · INQIMR Berghofer Medical Research Institute · AUThammasat University · THUniversity Hospital Cologne · DEUniversity of Bergen · NOYamagata Prefectural Central Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Overcoming colistin-resistant Acinetobacter baumannii (CoR-AB) has become a major concern due to the lack of effective antibiotics. This study aimed to explore the prevalence of CoR-AB clinical isolates in Thailand, their mechanisms of resistance, and test the efficacy of colistin plus sulbactam against CoR-AB isolates. The colistin resistance rate among carbapenem-resistant A. baumannii was 15.14%. The mcr gene or its variants were not detected in CoR-AB isolates by PCR screening. The lipid A mass spectra of CoR-AB isolates showed the additional [M-H]

Indexed as

Acinetobacter baumanniiAcinetobacter InfectionsColistinEthanolaminesHumansLipid AMicrobial Sensitivity TestsPhosphatidylethanolaminesSulbactamColistinEthanolaminesLipid APhosphatidylethanolaminesphosphorylethanolamineSulbactam

Identifiers

PMID35794134
PMCPMC9259700
OpenAlexW4283834800

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.