ArticleNeurospine2022
Current Trends in the Surgical Management of Intramedullary Tumors: A Multicenter Study of 1,033 Patients by the Neurospinal Society of Japan.
Article in Neurospine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 38 citations in OpenAlex.
- C2 Laminoplasty with Reconstruction of the Deep Extensor Muscles for Preventing Cervical Kyphosis after High Cervical Spinal Tumor Removal: Technical Notes.Neurologia medico-chirurgica · 2026Article
- Preoperative risk stratification for long-term neurological status in spinal ependymoma: an MRI-centered nomogram.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Clinical Characteristics, Management, and Outcomes of Intramedullary Spinal Cord Ependymomas: A Systematic Review and Meta-Analysis.Spine surgery and related research · 2026Review
- Clinical predictors of overall survival in pediatric patients with intramedullary spinal tumors: an analysis of the SEER database.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Article
- Impact of Cigarette Smoking on Clinical Outcomes after Surgical Resection in Patients with Intramedullary Spinal Cord Tumors: A Retrospective Comparative Study.Spine surgery and related research · 2026Article
- Comment on "Thoracic Intradural Extramedullary Cavernous Malformation Mimicking Meningioma".NMC case report journal · 2026Article
- Use of gross total resection and adjunctive therapy in treatment of spinal column tumors in low- and middle-income countries: A meta-analysis.Surgical neurology international · 2026Review
- Machine learning-driven national analysis for predicting adverse outcomes in intramedullary spinal cord tumor surgery.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- The Role of D-Wave Monitoring in Motor-Evoked Potential Loss During Intramedullary Spinal Cord Tumors Resection.Neurospine · 2025Article
- Article
- Long-level Intramedullary Spinal Cord Tumor: A Case Series.JNMA; journal of the Nepal Medical Association · 2025Article
- PRO-QOL after gross total resection of spinal ependymoma: a retrospective study based on 3-year follow-up observations in a single center.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- First-in-Human Trial of Photodynamic Therapy for Spinal Cord Malignant Astrocytoma: Study Protocol.Neurospine · 2024Article
- Nondysraphic intramedullary spinal cord lipoma: a case report.Annals of medicine and surgery (2012) · 2024Article
- Thoracic Intra and Extramedullary Capillary Hemangioma with Subacute Clinical Course: A Case Report and Literature Review.NMC case report journal · 2024Article
- The evolution of spinal cord surgery: history, people, instruments, and results.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Review
- Clinical Characteristics and Long-term Outcomes of Spinal Pilocytic Astrocytomas: A Multicenter Retrospective Study by the Neurospinal Society of Japan.Neurospine · 2023Article
- Article
- To Seek Appropriate Management for Intramedullary Spinal Cord Tumor: Commentary on Special Issue "Spinal Intramedullary Tumor".Neurospine · 2023Article
- Intramedullary Schwannoma of the Spinal Cord: A Nationwide Analysis by the Neurospinal Society of Japan.Neurospine · 2023Article
Corrections and comments
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Authors and funding
10 authors at 7 institutions in 1 country.
Funding
Abstract
objectiveWe performed a retrospective observational study to demonstrate the surgical risks and long-term prognoses of intramedullary tumors in Japan using a multicenter registry authorized by the Neurospinal Society of Japan.
methodsData from 1,033 consecutive patients with intramedullary tumors, treated between 2009 and 2020, were collected from 58 centers. Patients with spinal lipomas or myxopapillary ependymomas were excluded. Patient characteristics, clinical presentations, imaging characteristics, treatments, and outcomes were analyzed. The modified McCormick scale was used to classify functional status. Survival was described using Kaplan-Meier curves, and multivariable logistic regression analyses were performed.
resultsThe mean age of the patients was 48.4 years. Data of 361 ependymomas, 196 hemangioblastomas, 168 astrocytic tumors, 160 cavernous malformations, and the remaining 126 cases including subependymomas, metastases, schwannomas, capillary hemangiomas, and intravascular B-cell lymphomas were analyzed. Twenty-two patients were undiagnosed. The mean follow-up duration was 46.1 ± 38.5 months. Gross total tumor removal was achieved in 672 tumors (65.1%). On the modified McCormick scale, 234 patients (22.7%) had worse postoperative grades at the time of discharge. However, neurological status gradually improved. At 6 months postoperatively, 251 (27.5%), 500 (54.9%), and 160 patients (17.6%) had improved, unchanged, and worsened grades, respectively. Preoperative functional status, gross total tumor removal, and histopathological type were significantly associated with mortality and functional outcomes.
conclusionOur findings demonstrate better postoperative functional outcomes in patients with fewer preoperative neurological deficits. Degree of resection, postoperative treatments, and prognoses are closely related to the histology of intramedullary tumors.
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