Evidence map›Paper›PMID 35793918›Full record

ArticleBMJ open2022

Effects of inulin-type fructans supplementation on cardiovascular disease risk factors: a protocol for a systematic review and meta-analysis of

Jhalok Ronjan Talukdar, Matthew Adam Cooper, Lyuba Lyutvyn, Dena Zeraatkar, Rahim Ali, Rachel Bierbrier, Sabrina Janes, Vanessa Ha, Pauline B Darling, John L Sievenpiper and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 10 institutions in 4 countries.

Jhalok Ronjan TalukdarDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0001-9739-5632
Matthew Adam CooperDepartment of Medicine, University of Alberta, Edmonton, Alberta, Canada.
Lyuba LyutvynDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.
Dena ZeraatkarDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0003-4287-0541
Rahim AliFaculty of Law (Common Law Section), University of Ottawa, Ottawa, Ontario, Canada.
Rachel BierbrierDepartment of Dermatology, McGill University Health Centre, Montreal, Québec, Canada.
Sabrina JanesSt Michael's Hospital, Toronto, Ontario, Canada.
Vanessa HaSchool of Medicine, Faculty of Health Sciences, Queen's University, Kingston, Ontario, Canada.
Pauline B DarlingSchool of Nutrition Sciences, University of Ottawa, Ottawa, Ontario, Canada.
John L SievenpiperDepartment of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
David J A JenkinsDepartment of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0003-1192-9571
Laura BanfieldHealth Sciences Library, McMaster University, Hamilton, Ontario, Canada.
Lawrence MbuagbawDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0001-5855-5461
Russell J de SouzaDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada desouzrj@mcmaster.ca.ORCID 0000-0001-8945-513X
St. Michael's Hospital · CAImpact · CAUniversity of Ottawa · CAHarvard University · USMcGill University Health Centre · CAMcMaster University · CAPopulation Health Research Institute · CAQueen's University · CAStellenbosch University · ZAUniversity of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis review aims to assess the effects of dietary supplementation with inulin-type fructans (ITF) compared with no supplementation on cardiovascular disease risk factors in adults and assess the quality of trial reporting using the Consolidated Standards of Reporting Trials (CONSORT) and CONSORT for abstract (CONSORT-A) checklists. METHODS AND ANALYSIS: We will search randomised controlled trials (RCTs) in MEDLINE, EMBASE, CINAHL, Emcare, AMED and the Cochrane Database of Systematic Reviews from inception to 31 March 2022, without any language restrictions. The RCTs need to administer ITF in adults for at least 2 weeks and assess effects on at least one cardiovascular risk factor. We will exclude RCTs that (1) assessed the postprandial effects of ITF; (2) included pregnant or lactating participants; (3) enrolled participants undergoing treatment that might affect the response to ITF. We will assess the study risk of bias (RoB) using V.2 of the Cochrane RoB tool for RCTs (RoB 2) and the certainty of the evidence using the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) approach. We will pool data using a random-effects model. We will use the χ ETHICS AND DISSEMINATION: Ethics approval is not required for secondary analysis of already published data. We will publish the reviews in a peer-review journal. PROSPERO REGISTRATION NUMBER: CRD42019136745.

Indexed as

Cardiovascular DiseasesFructansAdultHumansInulinMeta-Analysis as TopicRandomized Controlled Trials as TopicSystematic Reviews as TopicFructansInulincoronary heart diseaseischaemic heart diseasenutrition

Identifiers

PMID35793918
PMCPMC9260802
OpenAlexW4284892976

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.