Evidence map›Paper›PMID 35793875›Full record

ReviewJournal for immunotherapy of cancer2022

Imaging approaches and radiomics: toward a new era of ultraprecision radioimmunotherapy?

Roger Sun, Théophraste Henry, Adrien Laville, Alexandre Carré, Anthony Hamaoui, Sophie Bockel, Ines Chaffai, Antonin Levy, Cyrus Chargari, Charlotte Robert and 1 more

Abstract readReview
In one paragraph

Review in Journal for immunotherapy of cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Trial
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  3. Value of [European journal of nuclear medicine and molecular imaging · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Roger SunDepartment of Radiation Oncology, Gustave Roussy, Villejuif, France.ORCID 0000-0001-9866-6449
Théophraste HenryRadiothérapie Moléculaire et Innovation Thérapeutique, Université Paris-Saclay, Institut Gustave Roussy, Inserm, Villejuif, France.ORCID 0000-0003-0672-415X
Adrien LavilleRadiothérapie Moléculaire et Innovation Thérapeutique, Université Paris-Saclay, Institut Gustave Roussy, Inserm, Villejuif, France.
Alexandre CarréRadiothérapie Moléculaire et Innovation Thérapeutique, Université Paris-Saclay, Institut Gustave Roussy, Inserm, Villejuif, France.
Anthony HamaouiRadiothérapie Moléculaire et Innovation Thérapeutique, Université Paris-Saclay, Institut Gustave Roussy, Inserm, Villejuif, France.
Sophie BockelDepartment of Radiation Oncology, Gustave Roussy, Villejuif, France.
Ines ChaffaiRadiothérapie Moléculaire et Innovation Thérapeutique, Université Paris-Saclay, Institut Gustave Roussy, Inserm, Villejuif, France.
Antonin LevyDepartment of Radiation Oncology, Gustave Roussy, Villejuif, France.
Cyrus ChargariRadiothérapie Moléculaire et Innovation Thérapeutique, Université Paris-Saclay, Institut Gustave Roussy, Inserm, Villejuif, France.
Charlotte RobertDepartment of Radiation Oncology, Gustave Roussy, Villejuif, France.ORCID 0000-0001-8838-1343
Eric DeutschDepartment of Radiation Oncology, Gustave Roussy, Villejuif, France eric.deutsch@gustaveroussy.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Strong rationale and a growing number of preclinical and clinical studies support combining radiotherapy and immunotherapy to improve patient outcomes. However, several critical questions remain, such as the identification of patients who will benefit from immunotherapy and the identification of the best modalities of treatment to optimize patient response. Imaging biomarkers and radiomics have recently emerged as promising tools for the non-invasive assessment of the whole disease of the patient, allowing comprehensive analysis of the tumor microenvironment, the spatial heterogeneity of the disease and its temporal changes. This review presents the potential applications of medical imaging and the challenges to address, in order to help clinicians choose the optimal modalities of both radiotherapy and immunotherapy, to predict patient's outcomes and to assess response to these promising combinations.

Indexed as

Diagnostic ImagingRadioimmunotherapyHumansImmunologic FactorsImmunotherapyPrecision MedicineImmunologic Factorsimmunotherapyradioimmunotherapyradiotherapytumor biomarkers

Identifiers

PMID35793875
PMCPMC9260846

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.