ArticleThyroid : official journal of the American Thyroid Association2022
Preoperative Identification of Medullary Thyroid Carcinoma (MTC): Clinical Validation of the Afirma MTC RNA-Sequencing Classifier.
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In one paragraph
Article in Thyroid : official journal of the American Thyroid Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
3.3field-weighted citation impact, top 6% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Beyond genomics: artificial intelligence-powered diagnostics for indeterminate thyroid nodules-a systematic review and meta-analysis.Frontiers in endocrinology · 2025Pooled it
- From Bench-to-Bedside: How Artificial Intelligence is Changing Thyroid Nodule Diagnostics, a Systematic Review.The Journal of clinical endocrinology and metabolism · 2024Pooled it
- The Diagnostic Performance of Afirma Genomic Sequencing Classifier in Black and Hispanic Patients With Indeterminate Thyroid Nodules.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026Article
- The Management of Medullary Thyroid Cancer: A Review.Annals of surgical oncology · 2026Review
- The diagnostic challenges of medullary thyroid carcinoma: A practical guide for cytopathologists.Cancer cytopathology · 2025Review
- What Is New in Diagnostics and Management of Medullary Thyroid Carcinoma.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2025Review
- Epidemiology, Clinical Presentation, and Diagnosis of Medullary Thyroid Carcinoma.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2025Review
- Review
- Article
- Review
- New Opportunities for Preoperative Diagnosis of Medullary Thyroid Carcinoma.Biomedicines · 2023Article
- Development and validation of an RNA sequencing-based classifier for medullary thyroid carcinoma on thyroid FNA.Cancer cytopathology · 2023Article
- Molecular diagnostics in the evaluation of thyroid nodules: Current use and prospective opportunities.Frontiers in endocrinology · 2023Review
- Enhancing Detection of Medullary Thyroid Cancer in Cytologically Indeterminate Thyroid Nodules: The Role of Molecular Testing.AACE endocrinology and diabetesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors at 14 institutions in 1 country.
Gregory W RandolphDivision of Thyroid and Parathyroid Endocrine Surgery, Department of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, USA.
Julie Ann SosaDepartment of Surgery, University of California San Francisco (UCSF), San Francisco, California, USA.
Yangyang HaoDepartment of Research and Development, Veracyte, Inc., South San Francisco, California, USA.
Trevor E AngellDivision of Endocrinology and Diabetes, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
David C ShonkaDepartment of Otolaryngology-Head and Neck Surgery, University of Virginia, Charlottesville, Virginia, USA.
Virginia A LiVolsiAnatomic Pathology Division, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.
Paul W LadensonDivision of Endocrinology, Diabetes and Metabolism, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Thomas C BlevinsTexas Diabetes and Endocrinology, Austin, Texas, USA.
Quan-Yang DuhSection of Endocrine Surgery, Department of Surgery, University of California San Francisco, San Francisco, California, USA.ORCID 0000-0002-7947-4393
Ronald GhosseinDepartment of Pathology and Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
Mack HarrellThe Memorial Center for Integrative Endocrine Surgery, Hollywood, Weston and Boca Raton, Florida, USA.
Kepal Narendra PatelDivision of Endocrine Surgery, Department of Surgery, NYU Langone Medical Center, New York, New York, USA.
Michael H ShanikEndocrine Associates of Long Island, Smithtown, New York, USA.
S Thomas TraweekThyroid Cytopathology Partners, Austin, Texas, USA.
P Sean WalshDepartment of Research and Development, Veracyte, Inc., South San Francisco, California, USA.
Michael W YehSection of Endocrine Surgery, UCLA David Geffen School of Medicine, Los Angeles, California, USA.
Amr H Abdelhamid AhmedDivision of Thyroid and Parathyroid Endocrine Surgery, Department of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0001-5611-5833
Allen S HoDepartment of Otolaryngology, Cedars-Sinai Medical Center, Los Angeles, California, USA.ORCID 0000-0001-5423-509X
Richard J WongHead and Neck Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
Joshua P KlopperDepartment of Medical Affairs, Veracyte, Inc., South San Francisco, California, USA.
Jing HuangDepartment of Research and Development, Veracyte, Inc., South San Francisco, California, USA.
Giulia C KennedyDepartment of Research and Development, Veracyte, Inc., South San Francisco, California, USA.
Richard T KloosDepartment of Medical Affairs, Veracyte, Inc., South San Francisco, California, USA.ORCID 0000-0003-4183-7387
Peter M SadowDepartment of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Veracyte (United States) · USMassachusetts Eye and Ear Infirmary · USMemorial Sloan Kettering Cancer Center · USUniversity of California, San Francisco · USA.M. Surgical (United States) · USCedars-Sinai Medical Center · USJohns Hopkins University · USMemorial Regional Hospital · USNYU Langone Health · USTexas Diabetes & Endocrinology · USUniversity of California, Los Angeles · USUniversity of Pennsylvania · USUniversity of Southern California · USUniversity of Virginia · US
Funding
Strategies to Overcome Immune Resistance in Head and Neck CancersP01CA240239 · NCI · YALE UNIVERSITY · PI PAI, SARA ISABEL · 2019 to 2023
$8.4MNCI NIH HHS P01 CA240239
Abstract
PubMed holds no abstract for this paper.
Indexed as
Thyroid NeoplasmsThyroid NoduleBiopsy, Fine-NeedleCarcinoma, NeuroendocrineGene Expression ProfilingHumansRetrospective StudiesRNAThyroid Cancer, PapillaryRNAindeterminate cytologymachine learningmedullary thyroid cancermolecular diagnosticsmolecular testingthyroid nodule
Identifiers
What OpenQuestion holds
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LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.