Evidence map›Paper›PMID 35792961›Full record

ArticleGeroScience2022

Brain age estimation reveals older adults' accelerated senescence after traumatic brain injury.

Anar Amgalan, Alexander S Maher, Satyaki Ghosh, Helena C Chui, Paul Bogdan, Andrei Irimia

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in GeroScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

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  10. Deep learning to quantify the pace of brain aging in relation to neurocognitive changes.Proceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Anar Amgalan *Ethel Percy Andrus Gerontology Center, Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.ORCID 0000-0001-8210-5030
Alexander S Maher *Ethel Percy Andrus Gerontology Center, Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.ORCID 0000-0003-4140-6085
Satyaki GhoshEthel Percy Andrus Gerontology Center, Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.
Helena C ChuiDepartment of Neurology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Paul BogdanMing Hsieh Department of Electrical and Computer Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, CA, USA.
Andrei IrimiaEthel Percy Andrus Gerontology Center, Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA. irimia@usc.edu.ORCID 0000-0002-9254-9388
University of Southern California · US

Funding

USCADRC Diversity Supplement PachicanoP30AG066530 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HELENA Chang CHUI, ARTHUR W TOGA · 2020 to 2026
$27.8M
Effects of blood-brain barrier disruption upon white matter connectivity subsequent to traumatic brain injuryR01NS100973 · NINDS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI IRIMIA, ANDREI · 2017 to 2021
$1.6M
NIA NIH HHS P30 AG066530NINDS NIH HHS R01 NS100973
6 · The paper itself

Abstract

Adults aged 60 and over are most vulnerable to mild traumatic brain injury (mTBI). Nevertheless, the extent to which chronological age (CA) at injury affects TBI-related brain aging is unknown. This study applies Gaussian process regression to T

Indexed as

AgingBrain Injuries, TraumaticAgedBrainFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedBiological ageChronological ageMachine learningMagnetic resonance imagingNeurodegeneration

Identifiers

PMID35792961
PMCPMC9768106
OpenAlexW4283835272

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.