ArticleThe Plant cell2022
The plant TOR kinase tunes autophagy and meristem activity for nutrient stress-induced developmental plasticity.
Article in The Plant cell, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 37 citations in OpenAlex.
- Methylthioadenosine-driven rewiring of sulfur assimilation lowers the methyl index and fertility in Arabidopsis.Journal of experimental botany · 2026Article
- Hidden players in plant response to sulfur deficit and beyond: insights into the function of the proteins Sulfur Deficiency Induced and Response to Low Sulfur.Journal of experimental botany · 2026Review
- Organelle-specific hydrogen sulfide metabolism governs redox homeostasis to regulate plant autophagy and cadmium stress resilience.Redox biology · 2026Article
- Review
- Sugar Transport and Signaling in Shoot Branching.International journal of molecular sciences · 2024Review
- Changes in cell wall composition due to a pectin biosynthesis enzyme GAUT10 impact root growth.Plant physiology · 2023Article
- Article
- Regulation of early seedling establishment and root development in Arabidopsis thaliana by light and carbohydrates.Planta · 2023Article
- New insights into the regulation of plant metabolism by O-acetylserine: sulfate and beyond.Journal of experimental botany · 2023Article
- ARSK1 activates TORC1 signaling to adjust growth to phosphate availability in Arabidopsis.Current biology : CB · 2023Article
- Role of autophagy-related proteins ATG8f and ATG8h in the maintenance of autophagic activity inFrontiers in plant science · 2023Article
- Recent insights into metabolic and signalling events of directional root growth regulation and its implications for sustainable crop production systems.Frontiers in plant science · 2023Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plants, unlike animals, respond to environmental challenges with comprehensive developmental transitions that allow them to cope with these stresses. Here we discovered that antagonistic activation of the Target of Rapamycin (TOR) kinase in Arabidopsis thaliana roots and shoots is essential for the nutrient deprivation-induced increase in the root-to-shoot ratio to improve foraging for mineral ions. We demonstrate that sulfate limitation-induced downregulation of TOR in shoots activates autophagy, resulting in enhanced carbon allocation to the root. The allocation of carbon to the roots is facilitated by the specific upregulation of the sucrose-transporter genes SWEET11/12 in shoots. SWEET11/12 activation is indispensable for enabling sucrose to act as a carbon source for growth and as a signal for tuning root apical meristem activity via glucose-TOR signaling. The sugar-stimulated TOR activity in the root suppresses autophagy and maintains root apical meristem activity to support root growth to enhance mining for new sulfate resources in the soil. We provide direct evidence that the organ-specific regulation of autophagy is essential for the increased root-to-shoot ratio in response to sulfur limitation. These findings uncover how sulfur limitation controls the central sensor kinase TOR to enable nutrient recycling for stress-induced morphological adaptation of the plant body.
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