ArticleNano letters2022
Intracellular Heat Transfer and Thermal Property Revealed by Kilohertz Temperature Imaging with a Genetically Encoded Nanothermometer.
Article in Nano letters, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Non-diffusive slow heat dissipation induces high local temperature in living cells.Nature communications · 2026Article
- Upconversion Photoluminescence to Monitor Local Heat Release During Femtosecond Direct Laser Writing of Bioinks In Situ.Small methods · 2026Article
- All-optical diamond heater-thermometer enables versatile and reliable thermal modulation of ion channels at the single-cell level.Biophysical journal · 2026Article
- Millikelvin Intracellular Nanothermometry with Nanodiamonds.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Ratiometric Boltzmann thermometry with CrLight, science & applications · 2025Article
- Magnetic nanomaterials for hyperthermia-based therapy and controlled drug delivery.Bioactive materials · 2025Review
- A Thermogenetic Tool Employing Elastin-like Polypeptides for Controlling Programmed Cell Death.ACS nano · 2025Article
- Genetically-encoded temperature indicators for thermal biology.Biophysics and physicobiology · 2025Article
- Heat application in live cell imaging.FEBS open bio · 2024Review
- Mitochondria: great balls of fire.The FEBS journal · 2024Review
- Molecular Spies in Action: Genetically Encoded Fluorescent Biosensors Light up Cellular Signals.Chemical reviews · 2024Review
- Infrared laser-induced gene expression in single cells characterized by quantitative imaging in Physcomitrium patens.Communications biology · 2024Article
- Extremely Sensitive Genetically Encoded Temperature Indicator Enabling Measurement at the Organelle Level.ACS sensors · 2024Article
- Article
- Review
- Local Temperature Increments and Induced Cell Death in Intracellular Magnetic Hyperthermia.ACS nano · 2023Article
- Real-Time Temperature Sensing Using a Ratiometric Dual Fluorescent Protein Biosensor.Biosensors · 2023Article
- Quantum nanodiamonds for sensing of biological quantities: Angle, temperature, and thermal conductivity.Biophysics and physicobiology · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite improved sensitivity of nanothermometers, direct observation of heat transport inside single cells has remained challenging for the lack of high-speed temperature imaging techniques. Here, we identified insufficient temperature resolution under short signal integration time and slow sensor kinetics as two major bottlenecks. To overcome the limitations, we developed B-gTEMP, a nanothermometer based on the tandem fusion of mNeonGreen and tdTomato fluorescent proteins. We visualized the propagation of heat inside intracellular space by tracking the temporal variation of local temperature at a time resolution of 155 μs and a temperature resolution 0.042 °C. By comparing the fast
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.