ArticleEuropean heart journal. Acute cardiovascular care2022
New-onset atrial fibrillation in intensive care: epidemiology and outcomes.
Article in European heart journal. Acute cardiovascular care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review on the influence of coagulopathy and immune activation on New Onset Atrial Fibrillation in patients with sepsis.PloS one · 2025Pooled it
- Clinical subtypes and prognosis of new-onset atrial fibrillation in critically ill patients.International journal of cardiology. Cardiovascular risk and prevention · 2026Article
- Association Between Endogenous Ketosis and Risk of Atrial Fibrillation in Intensive Care Versus General Ward Patients: A Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- A prospective, multi-site, observational study assessing the treatment thresholds of new onset atrial fibrillation in the critically ill.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2026Article
- Impact of heart rate on Doppler echocardiography predictors of rhythm control in patients with septic shock.Scientific reports · 2026Article
- Epidemiology and pharmacological management of new onset atrial fibrillation in critically ill adults: A multicentre observational study.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2026Article
- Machine Learning Prediction of ICU Mortality and Length of Stay in Atrial Fibrillation: A MIMIC-IV/MIMIC-III Study.Healthcare (Basel, Switzerland) · 2026Article
- 2025 Thai guideline for the diagnosis and management of atrial fibrillation.Asian biomedicine : research, reviews and news · 2025Article
- Association between heart rate fluctuation and mortality in intensive care patients with atrial fibrillation.Scientific reports · 2025Article
- Atrial fibrillation in critical illness: state of the art.Intensive care medicine · 2025Review
- Detection of Atrial Fibrillation in Holter ECG Recordings by ECHOView Images: A Deep Transfer Learning Study.Diagnostics (Basel, Switzerland) · 2025Article
- Optimizing clinical prediction model for new-onset atrial fibrillation in critically ill patient: Based on machine learning.PloS one · 2025Article
- Spotlight on the 2024 ESC/EACTS management of atrial fibrillation guidelines: 10 novel key aspects.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024Review
- Research priorities for the study of atrial fibrillation during acute and critical illness: recommendations from the Symposium on Atrial Fibrillation in Acute and Critical Care.BMC proceedings · 2024Article
- Interpretable machine learning model for new-onset atrial fibrillation prediction in critically ill patients: a multi-center study.Critical care (London, England) · 2024Article
- An International Survey of the Management of Atrial Fibrillation in Critically Unwell Patients.Critical care explorations · 2024Article
- Management of supraventricular arrhythmias in the intensive care unit: a step in the right direction.Intensive care medicine · 2023Article
- Article
- Association of Mitral Regurgitation with Postoperative Atrial Fibrillation in Critically Ill Noncardiac Surgery Patients: A Prospective Cohort Study.International journal of general medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
aimsNew-onset atrial fibrillation (NOAF) is common in patients treated on an intensive care unit (ICU), but the long-term impacts on patient outcomes are unclear. We compared national hospital and long-term outcomes of patients who developed NOAF in ICU with those who did not, before and after adjusting for comorbidities and ICU admission factors. METHODS AND
resultsUsing the RISK-II database (Case Mix Programme national clinical audit of adult intensive care linked with Hospital Episode Statistics and mortality data), we conducted a retrospective cohort study of 4615 patients with NOAF and 27 690 matched controls admitted to 248 adult ICUs in England, from April 2009 to March 2016. We examined in-hospital mortality; hospital readmission with atrial fibrillation (AF), heart failure, and stroke up to 6 years post discharge; and mortality up to 8 years post discharge. Compared with controls, patients who developed NOAF in the ICU were at a higher risk of in-hospital mortality [unadjusted odds ratio (OR) 3.22, 95% confidence interval (CI) 3.02-3.44], only partially explained by patient demographics, comorbidities, and ICU admission factors (adjusted OR 1.50, 95% CI 1.38-1.63). They were also at a higher risk of subsequent hospitalization with AF [adjusted cause-specific hazard ratio (aCHR) 5.86, 95% CI 5.33-6.44], stroke (aCHR 1.47, 95% CI 1.12-1.93), and heart failure (aCHR 1.28, 95% CI 1.14-1.44) independent of pre-existing comorbidities.
conclusionPatients who develop NOAF during an ICU admission are at a higher risk of in-hospital death and readmissions to hospital with AF, heart failure, and stroke than those who do not.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.