Evidence map›Paper›PMID 35792133›Full record

ReviewChemical Society reviews2022

Lanthanide porphyrinoids as molecular theranostics.

Guo-Qing Jin, Calvin V Chau, Jonathan F Arambula, Song Gao, Jonathan L Sessler, Jun-Long Zhang

Abstract readReview
In one paragraph

Review in Chemical Society reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Recent progress in the exploitation of anti-cancer small molecules targeting angiogenesis.Journal of enzyme inhibition and medicinal chemistry · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Rare Earths-The Answer to Everything.Molecules (Basel, Switzerland) · 2024
    Review
  15. Nickel(II) Phototheranostics: A Case Study in Photoactivated HJournal of the American Chemical Society · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Nontoxic TbRSC advances · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Guo-Qing JinBeijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, P. R. China. zhangjunlong@pku.edu.cn.ORCID http://orcid.org/0000-0001-9795-0149
Calvin V ChauDepartment of Chemistry, The University of Texas at Austin, Austin, Texas 78712-1224, USA. sessler@cm.utexas.edu.ORCID http://orcid.org/0000-0003-2479-8590
Jonathan F ArambulaDepartment of Chemistry, The University of Texas at Austin, Austin, Texas 78712-1224, USA. sessler@cm.utexas.edu.ORCID http://orcid.org/0000-0003-2342-8440
Song GaoBeijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, P. R. China. zhangjunlong@pku.edu.cn.ORCID http://orcid.org/0000-0002-0039-6346
Jonathan L SesslerDepartment of Chemistry, The University of Texas at Austin, Austin, Texas 78712-1224, USA. sessler@cm.utexas.edu.ORCID http://orcid.org/0000-0002-9576-1325
Jun-Long ZhangBeijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, P. R. China. zhangjunlong@pku.edu.cn.ORCID http://orcid.org/0000-0002-5731-7354

Funding

Biomedical Applications of Expanded Porphyrins: Development of Gold-Texaphyrin ConjugatesR01CA068682 · NCI · UNIVERSITY OF TEXAS AUSTIN · PI Esther Y. Maier, Emily L Que · 1995 to 2026
$7.4M
NCI NIH HHS R01 CA068682
6 · The paper itself

Abstract

In recent years, lanthanide (Ln) porphyrinoids have received increasing attention as theranostics. Broadly speaking, the term 'theranostics' refers to agents designed to allow both disease diagnosis and therapeutic intervention. This Review summarises the history and the 'state-of-the-art' development of Ln porphyrinoids as theranostic agents. The emphasis is on the progress made within the past decade. Applications of Ln porphyrinoids in near-infrared (NIR, 650-1700 nm) fluorescence imaging (FL), magnetic resonance imaging (MRI), radiotherapy, and chemotherapy will be discussed. The use of Ln porphyrinoids as photo-activated agents ('phototheranostics') will also be highlighted in the context of three promising strategies for regulation of porphyrinic triplet energy dissipation pathways, namely: regioisomeric effects, metal regulation, and the use of expanded porphyrinoids. The goal of this Review is to showcase some of the ongoing efforts being made to optimise Ln porphyrinoids as theranostics and as phototheranostics, in order to provide a platform for understanding likely future developments in the area, including those associated with structure-based innovations, functional improvements, and emerging biological activation strategies.

Indexed as

Lanthanoid Series ElementsMagnetic Resonance ImagingPrecision MedicineTheranostic NanomedicineLanthanoid Series Elements

Identifiers

PMID35792133
PMCPMC12005637

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.