ArticleVeterinary clinical pathology2022
Establishment of a reference interval for urinary albumin-to-creatinine ratio in dogs.
Article in Veterinary clinical pathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Clinico-pathological and renal morphological findings in dogs naturally infected with Dirofilaria repens.BMC veterinary research · 2026Article
- Renal Biomarkers in Companion Animals-A Review.Animals : an open access journal from MDPI · 2025Review
- Effects of Exercise on Urinary Parameters and Proteins in Well-Trained Canicross Dogs: A Preliminary Study.Animals : an open access journal from MDPI · 2024Article
- Diagnostic validation of the urine albumin-to-creatinine ratio for early renal disease in healthy dogs and dogs with chronic kidney disease.Journal of veterinary science · 2024Article
- A comprehensive analysis of albuminuria in canine chronic kidney disease.Veterinary medicine and science · 2024Article
- Effects of exercise on urinary biochemical parameters and proteins in a group of well-trained military working dogs.The veterinary quarterly · 2023Article
- Establishment of a reference interval for urinary albumin-to-creatinine ratio in dogs.Veterinary clinical pathology · 2022Article
- Longitudinal Study of Renal Health Screening in Apparently Healthy Aging Dogs.Journal of veterinary internal medicineArticle
- Albuminuria and proteinuria in dogs infected with Dirofilaria repens: A cross-sectional study.Journal of veterinary internal medicineArticle
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Authors and funding
7 authors.
Funding
Abstract
backgroundAlbuminuria is an important marker of renal damage and can precede proteinuria; thus, it can be a useful analyte in the early diagnosis of kidney diseases. Albuminuria has also been found in dogs with hypertension, inflammatory, infectious, and neoplastic diseases.
objectivesThe aim of this study was to establish a reference interval (RI) for albuminuria in dogs.
methodsOne hundred sixty-four clinically healthy dogs were enrolled in the study. Urinary albumin was determined by the immunoturbidimetric method, and albumin excretion was expressed as the urinary albumin-to-creatinine (UAC) ratio. The RI for UAC was established.
resultsAfter exclusions, 124 dogs from 32 breeds remained. The median UAC of the study population was 3.0 mg/g (range: 0-48). The RI was defined as 0-19 mg/g (with a 90% CI for the upper limit of 13-28 mg/g). No significant difference was found between male and female dogs or between different age and body weight groups. The results of Sighthounds (n = 30) and Beagle dogs (n = 23) did not differ from the other breeds.
conclusionThe canine RI of UAC is similar but somewhat narrower than the human RI.
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