ArticleJournal of clinical hypertension (Greenwich, Conn.)2022
Nighttime mean arterial pressure is associated with left ventricular hypertrophy in white-coat hypertension.
Article in Journal of clinical hypertension (Greenwich, Conn.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 5 citations in OpenAlex.
- Association between ambulatory blood pressure monitoring parameters and left ventricular hypertrophy in an Ecuadorian population.Frontiers in medicine · 2026Article
- Left ventricular hypertrophy in hypertension: Need of ethnic-specific criteria.Journal of clinical hypertension (Greenwich, Conn.) · 2022Article
- Nighttime mean arterial pressure is associated with left ventricular hypertrophy in white-coat hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2022Article
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9 authors at 2 institutions in 1 country.
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Abstract
White-coat hypertension (WCH) is associated with increased cardiovascular risks. To investigate the relationship between WCH and left ventricular hypertrophy (LVH), the authors recruited 706 participants who underwent anthropometric measurements, blood laboratory analysis, 24h ambulatory blood pressure monitoring (ABPM), and echocardiography. The authors defined WCH as elevated office BP but normal ABPM over 24h, daytime, and nighttime periods. The authors compared the proportion of LVH between the true normotension (NT) and the WCH population, and further assessed the associations between BP indexes and LVH in the two groups, respectively. The proportion of LVH was significantly higher in the WCH group than in NT participants (19.70% vs. 13.12%, P = .036). In the NT group, 24h SBP, 24h PP, daytime SBP, daytime PP and SD of nighttime SBP were associated with LVH after adjustment for demographic and blood biochemical data (all P < .05). In the WCH population, LVH was associated with 24h SBP, nighttime SBP, nighttime MAP, and office SBP after adjustment (all P < .05). However, on forward logistic regression analysis with all the BP indexes listed above, only 24h SBP (OR = 1.057, 1.017-1.098, P < .001) in the NT group, and nighttime MAP (OR = 1.114, 1.005-1.235, P < .05) and office SBP (OR = 1.067, 1.019-1.117, P < .001) in the WCH group were still significantly associated with LVH. Our study suggests that the proportion of LVH is higher in WCH patients than in the NT population. Furthermore, elevated nighttime MAP and office SBP may play critical roles in the development of LVH in the WCH population.
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