ArticleAcute and critical care2022
In-hospital mortality prediction using frailty scale and severity score in elderly patients with severe COVID-19.
Article in Acute and critical care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed, 15 citations in OpenAlex.
- Respiratory and Pleural Pathogens in Octogenarians Hospitalized with COVID-19: Impact of Secondary Bacterial Pneumonia on Day-5 SOFA and Mortality.Microorganisms · 2026Article
- Article
- Biological age and clinical frailty scale measured at intensive care unit admission as predictors of hospital mortality among the critically ill in Western Australia: a retrospective cohort study.Acute and critical care · 2025Article
- Prevalence of New Frailty at Hospital Discharge in Severe COVID-19 Survivors and Its Associated Factors.Tuberculosis and respiratory diseases · 2025Article
- Risk factors for progressing to critical illness in patients with hospital-acquired COVID-19.The Korean journal of internal medicine · 2024Article
- Risk Factors and Predictive Model for Mortality of Hospitalized COVID-19 Elderly Patients from a Tertiary Care Hospital in Thailand.Medicines (Basel, Switzerland) · 2023Article
- Modified Early Warning Score: Clinical Deterioration of Mexican Patients Hospitalized with COVID-19 and Chronic Disease.Healthcare (Basel, Switzerland) · 2023Article
- Neurological Manifestations and Complications of the Central Nervous System as Risk Factors and Predictors of Mortality in Patients Hospitalized with COVID-19: A Cohort Study.Journal of clinical medicine · 2023Article
- Atypical presentation of COVID-19 in older patients is associated with frailty but not with adverse outcomes.European geriatric medicine · 2023Article
- Evaluation of risk scores as predictors of mortality and hospital length of stay for older COVID-19 patients.Aging medicine (Milton (N.S.W)) · 2023Article
- Retrospective Study to Identify Risk Factors for Severe Disease and Mortality Using the Modified Early Warning Score in 5127 Patients with COVID-19 Admitted to an Emergency Department in Poland Between March 2020 and April 2021.Medical science monitor : international medical journal of experimental and clinical research · 2022Article
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Authors and funding
8 authors at 7 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundElderly patients with coronavirus disease 2019 (COVID-19) have a high disease severity and mortality. However, the use of the frailty scale and severity score to predict in-hospital mortality in the elderly is not well established. Therefore, in this study, we investigated the use of these scores in COVID-19 cases in the elderly.
methodsThis multicenter retrospective study included severe COVID-19 patients admitted to seven hospitals in Republic of Korea from February 2020 to February 2021. We evaluated patients' Acute Physiology and Chronic Health Evaluation (APACHE) II score; confusion, urea nitrogen, respiratory rate, blood pressure, 65 years of age and older (CURB-65) score; modified early warning score (MEWS); Sequential Organ Failure Assessment (SOFA) score; clinical frailty scale (CFS) score; and Charlson comorbidity index (CCI). We evaluated the predictive value using receiver operating characteristic (ROC) curve analysis.
resultsThe study included 318 elderly patients with severe COVID-19 of whom 237 (74.5%) were survivors and 81 (25.5%) were non-survivors. The non-survivor group was older and had more comorbidities than the survivor group. The CFS, CCI, APACHE II, SOFA, CURB-65, and MEWS scores were higher in the non-survivor group than in the survivor group. When analyzed using the ROC curve, SOFA score showed the best performance in predicting the prognosis of elderly patients (area under the curve=0.766, P<0.001). CFS and SOFA scores were associated with in-hospital mortality in the multivariate analysis.
conclusionsThe SOFA score is an efficient tool for assessing in-hospital mortality in elderly patients with severe COVID-19.
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