ArticleJournal of radiation research2022
Analysis of boron neutron capture reaction sensitivity using Monte Carlo simulation and proposal of a new dosimetry index in boron neutron capture therapy.
Article in Journal of radiation research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Development of Linear Interpolation System for SMK Model Parameters Evaluated from Cellular-Scale Simulation (LISMEC) and its application to BNCT dosimetry.Journal of radiation research · 2026Article
- Preliminary outcomes of boron neutron capture therapy for head and neck cancers as a treatment covered by public health insurance system in Japan: Real-world experiences over a 2-year period.Cancer medicine · 2024Article
- Pharmacokinetic Study ofEuropean journal of drug metabolism and pharmacokinetics · 2023Article
- Development of the Follow-Up Human 3D Oral Cancer Model in Cancer Treatment.Biotech (Basel (Switzerland)) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Boron neutron capture therapy is a cellular-scale heavy-particle therapy. The factor determining the biological effects in the boron neutron capture reaction (BNCR) is the value of ${\alpha}_{boron}$, which is the alpha component in the Linear Quadratic (LQ) model. Recently, the factor determining the value of ${\alpha}_{boron}$ has been revealed to correspond to the structural features of the tumor tissue. However, the relationship and mechanism have yet to be thoroughly studied. In this study, we simulated BNCR in tissues using the Monte Carlo simulation technique and examined the factors that determine the value of ${\alpha}_{boron}$. According to this simulation, the nuclear-cytoplasmic (N/C) ratio, nuclear diameter and heterogeneity of the distribution of boron in the tissue have been suggested to determine the value of ${\alpha}_{boron}$. Moreover, we proposed Biological Effectivity (BE) as a new dosimetry index based on the surviving fraction (SF), extending the concept of absolute biological effectiveness (ABE) in a previous report.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.