Evidence map›Paper›PMID 35791359›Full record

ArticleOpen forum infectious diseases2022

Health Care Workers' Sick Leave due to COVID-19 Vaccination in Context With SARS-CoV-2 Infection and Quarantine-A Multicenter Cross-Sectional Survey.

Stilla Bauernfeind, Gunnar Huppertz, Karolina Mueller, Florian Hitzenbichler, Loredana Hardmann, Sylvia Pemmerl, Harald Hollnberger, Wolfgang Sieber, Matthias Wettstein, Stephan Seeliger and 8 more

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Observational
  2. Article
  3. Avidity maturation of anti-spike IgG after vaccination in COVID-19 convalescent vs COVID-19 naïve patients.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 1 country.

Stilla BauernfeindDepartment of Infection Prevention and Infectious Diseases, University Medical Center Regensburg, Regensburg, Germany.ORCID https://orcid.org/0000-0002-4335-6942
Gunnar HuppertzCenter for Clinical Studies, University Medical Center Regensburg, Regensburg, Germany.
Karolina MuellerCenter for Clinical Studies, University Medical Center Regensburg, Regensburg, Germany.
Florian HitzenbichlerDepartment of Infection Prevention and Infectious Diseases, University Medical Center Regensburg, Regensburg, Germany.
Loredana HardmannDepartment of Infection Prevention and Infectious Diseases, University Medical Center Regensburg, Regensburg, Germany.
Sylvia PemmerlCaritas-Krankenhaus St. Josef, Regensburg, Germany.
Harald HollnbergerHospital St. Marien Amberg, Amberg, Germany.
Wolfgang SieberKreisklinik Woerth an der Donau, Woerth an der Donau, Germany.
Matthias WettsteinKlinikum Passau, Passau, Germany.
Stephan SeeligerSankt Elisabeth, KJF Klinik, Neuburg an der Donau, Germany.
Klaus KienleRottal-Inn Kliniken, Eggenfelden, Germany.
Christian PaetzelKliniken Nordoberpfalz AG, Weiden, Germany.
Norbert KutzGoldbergklinik Kelheim, Kelheim, Germany.
Dionys DallerKlinik Bogen, Bogen, Germany.
Niels ZorgerHospital of the Order of St. John of God Regensburg, Regensburg, Germany.
Arno MohrCenter for Pneumology, Donaustauf Hospital, Donaustauf, Germany.
Benedikt M J LamplDivision of Infection Control and Prevention, Regensburg Department of Public Health, Regensburg, Germany.ORCID https://orcid.org/0000-0002-1008-7934
Bernd SalzbergerDepartment of Infection Prevention and Infectious Diseases, University Medical Center Regensburg, Regensburg, Germany.
Klinik Donaustauf · DECaritas-Krankenhaus St. Josef · DEKlinikum Passau · DEKlinikum St. Marien Amberg · DEKlinikum Weiden · DEUniversity of Regensburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Reactogenicity of coronavirus disease 2019 (COVID-19) vaccines can result in inability to work. The object of this study was to evaluate health care workers' sick leave after COVID-19 vaccination and to compare it with sick leave due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and quarantine leave. Methods: A multicenter cross-sectional survey was conducted at Regensburg University Medical Center and 10 teaching hospitals in South-East Germany from July 28 to October 15, 2021. Results: Of 2662 participants, 2309 (91.8%) were fully vaccinated without a history of SARS-CoV-2 infection. Sick leave after first/second vaccination occurred in 239 (10.4%) and 539 (23.3%) participants. In multivariable logistic regression, the adjusted odds ratio for sick leave after first/second vaccination compared with BNT162b2 was 2.26/3.72 for mRNA-1237 (95% CI, 1.28-4.01/1.99-6.96) and 27.82/0.48 for ChAdOx1-S (95% CI, 19.12-40.48/0.24-0.96). The actual median sick leave (interquartile range [IQR]) was 1 (0-2) day after any vaccination. Two hundred fifty-one participants (9.4%) reported a history of SARS-CoV-2 infection (median sick leave [IQR] 14 [10-21] days), 353 (13.3%) were quarantined at least once (median quarantine leave [IQR], 14 [10-14] days). Sick leave due to SARS-CoV-2 infection (4642 days) and quarantine leave (4710 days) accounted for 7.7 times more loss of workforce than actual sick leave after first and second vaccination (1216 days) in all fully vaccinated participants. Conclusions: Sick leave after COVID-19 vaccination is frequent and is associated with the vaccine applied. COVID-19 vaccination should reduce the much higher proportion of loss of workforce due to SARS-CoV-2 infection and quarantine.

Indexed as

COVID-19quarantineSARS-CoV-2 infectionsick leavevaccine reactogenicity

Identifiers

PMID35791359
PMCPMC9047200
OpenAlexW4223971260

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.