Evidence map›Paper›PMID 35791355›Full record

ArticleOpen forum infectious diseases2022

Severe Acute Respiratory Syndrome Coronavirus 2 Seroprevalence Among HIV-Negative Participants Using Tenofovir/Emtricitabine-Based Preexposure Prophylaxis in 2020: A Substudy of the French National Agency for Research on AIDS and Viral Hepatitis PREVENIR and Inserm SAPRIS-Sero Cohorts.

Constance Delaugerre, Lambert Assoumou, Sarah Maylin, Marine Minier, Audrey Gabassi, Michèle Genin, Lydie Beniguel, Jade Ghosn, Xavier de Lamballerie, Mayssam El Mouhebb and 4 more

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Constance DelaugerreService de Virologie, Hôpital Saint Louis, Assistance Publique-Hôpitaux de Paris, Paris, France.
Lambert AssoumouSorbonne Université, Inserm, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Paris, France.
Sarah MaylinService de Virologie, Hôpital Saint Louis, Assistance Publique-Hôpitaux de Paris, Paris, France.
Marine MinierService de Virologie, Hôpital Saint Louis, Assistance Publique-Hôpitaux de Paris, Paris, France.
Audrey GabassiService de Virologie, Hôpital Saint Louis, Assistance Publique-Hôpitaux de Paris, Paris, France.
Michèle GeninSorbonne Université, Inserm, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Paris, France.
Lydie BeniguelSorbonne Université, Inserm, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Paris, France.
Jade GhosnService de Maladies infectieuses, Hôpital Bichat, Assistance Publique-Hôpitaux de Paris, Infection, Antimicrobials, Modelling, Evolution, Inserm, Université mixte de recherche 1137, Université de Paris, Paris, France.
Xavier de LamballerieUnité des Virus Emergents, Université Aix Marseille, Institut de recherche pour le développement 190, Inserm U1207, Marseille, France.
Mayssam El MouhebbSorbonne Université, Inserm, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Paris, France.
Dominique CostagliolaSorbonne Université, Inserm, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Paris, France.
Fabrice CarratSorbonne Université, Inserm, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Paris, France.ORCID https://orcid.org/0000-0002-8672-7918
Jean Michel MolinaUniversité de Paris, Inserm, U944, Paris, France.
PREVENIR and SAPRIS-Sero Study Groups
Inserm · FRAssistance Publique – Hôpitaux de Paris · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The potential preventive efficacy of tenofovir/emtricitabine on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was assessed in human immunodeficiency virus preexposure prophylaxis (PrEP) users. Prevalence of SARS-CoV-2 immunoglobulin G between May and October 2020 was similar in PrEP users and in a matched population-based cohort, suggesting that tenofovir/emtricitabine has no role in reducing the risk of SARS-CoV-2 acquisition.

Indexed as

HIVPrEPSARS-CoV-2

Identifiers

PMID35791355
PMCPMC9047207
OpenAlexW4223559869

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.