Evidence map›Paper›PMID 35791272›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2022

Association between the time of day at stroke onset and functional outcome of acute ischemic stroke patients treated with endovascular therapy.

Xian Wang, Xiaoyin Wang, Jin Ma, Milan Jia, Longfei Wu, Weili Li, Chuanhui Li, Chuanjie Wu, Changhong Ren, Xin Chen and 2 more

Abstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Circadian Neurology.Continuum (Minneapolis, Minn.) · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Larger ischemic cores and poor collaterals among large vessel occlusions presenting in the late evening.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2023
    Article
  14. Article
  15. Article
  16. Influence of Temperature Chronobiology on Stroke Outcome.International journal of molecular sciences · 2023
    Observational
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xian WangBeijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing, China.ORCID 0000-0002-8263-8010
Xiaoyin WangDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Jin MaDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Milan JiaDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Longfei WuDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-0954-9126
Weili LiBeijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing, China.
Chuanhui LiDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Chuanjie WuDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Changhong RenBeijing Key Laboratory of Hypoxic Conditioning Translational Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China.
Xin ChenDepartment of General Surgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Wenbo ZhaoBeijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing, China.
Xunming JiBeijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To investigate the association between time-of-day of stroke onset and functional outcome in patients with acute ischemic stroke(AIS) treated with endovascular thrombectomy(EVT). AIS patients treated with EVT between January 2013 and December 2018 were recruited and divided them into four 6-h interval groups according to the time-of-day of stroke onset. A total of 438 patients were enrolled, 3-month favorable outcome were achieved in 58.6%, 43.7%, 36.6%, and 30.5% of patients in the 00:00-06:00, 06:00-12:00, 12:00-18:00, and 18:00-24:00 groups, respectively (adjusted OR 0.61, 95% CI 0.40-0.93;

Indexed as

Brain IschemiaEndovascular ProceduresIschemic StrokeStrokeHumansThrombectomyTreatment Outcomecircadian rhythmendovascular therapyfunctional outcomeIschemic stroketime of day

Identifiers

PMID35791272
PMCPMC9670006

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.