ReviewDeutsches Arzteblatt international2022
Multimodal Treatment of Rectal Cancer.
Review in Deutsches Arzteblatt international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- [Combination of radiotherapy and medicinal anticancer therapy with curative intent].Radiologie (Heidelberg, Germany) · 2026Article
- Patient-reported outcomes in low anterior resection syndrome: a comparison of open and robotic surgery.International journal of colorectal disease · 2026Article
- Targeting metabolic dependencies to reverse chemoradiotherapy resistance in colorectal cancer.Journal of experimental & clinical cancer research : CR · 2026Article
- Pretreatment MRI: One of the Key Components of Treatment Planning.Deutsches Arzteblatt international · 2026Article
- Effectiveness and outcome of gracilis muscle flap reconstruction following perineal surgery: a retrospective single-center cohort study.Annals of medicine and surgery (2012) · 2026Article
- Pan-ERBB Inhibitors Synergize With KRAS Inhibitors in Rectal Cancer.United European gastroenterology journal · 2025Article
- Splenic flexure resection with Hugo™ RAS: Trocar placement, docking settings, and surgical strategy.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025Article
- Education and Symptom Reporting in an mHealth App for Patients With Cancer: Mixed Methods Development and Validation Study.JMIR human factors · 2025Article
- Tumor-associated macrophage expression in colorectal adenomas and carcinomas: relationship toFrontiers in oncology · 2025Article
- Article
- Change in Quality of Life in Patients with Advanced Rectal Cancer Between 2010 and 2022.Healthcare (Basel, Switzerland) · 2024Article
- [A 5-year follow-up of the RAPIDO trial: Back to the future of long-course radiochemotherapy in total neoadjuvant treatment (TNT) for locally advanced rectal cancer?]Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2024Article
- Elderly Rectal Cancer: An Updated Review.Current oncology reports · 2024Review
- Immunotherapy for colorectal cancer.Frontiers in immunology · 2024Review
- Prognostic value of the ratio of pretreatment carcinoembryonic antigen to tumor volume in rectal cancer.Journal of gastrointestinal oncology · 2023Article
- Impact of COVID-19 on Quality of Life in Long-Term Advanced Rectal Cancer Survivors.Healthcare (Basel, Switzerland) · 2023Article
- Prognostic and Predictive Value of Pan-Immune Inflammation Value in Rectal Cancer Patients Treated With Neoadjuvant Therapy.Cancer control : journal of the Moffitt Cancer CenterArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundColorectal cancer is one of the three most common types of cancer in Germany. Approximately 30% of these cancers are located in the rectum, corresponding to about 18 000 new cases per year.
methodsThis review is based on publications retrieved by a selective search in the PubMed database, including current guidelines and recommendations.
resultsSpecialized imaging, particularly magnetic resonance imaging, is essential for treatment planning. In very early stages of this disease, tumors without risk factors can be excised locally. Otherwise, radical surgical resection with lymphadenectomy remains the standard treatment, and can be performed either minimally invasive or open. At present, neoadjuvant treatment plans are evolving in the direction of total neoadjuvant therapy. In addition, recent studies investigate whether the improved efficacy of neoadjuvant therapy might now enable patients with a complete clinical remission to be spared from surgical resection (organ-preserving watch-and-wait strategy).
conclusionThe treatment of rectal cancer is a prime example of an interdisciplinary, multimodal approach. In the past, the focus was mainly on improving oncologic outcomes; at present, increasing attention is being devoted to the patients' quality of life as well and the functional aspects of the various modes of treatment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.