Evidence map›Paper›PMID 35791065›Full record

ArticleEuropean journal of heart failure2022

An international Delphi consensus regarding best practice recommendations for hyperkalaemia across the cardiorenal spectrum.

James O Burton, Andrew J S Coats, Csaba P Kovesdy, Biff F Palmer, Ileana L Piña, Giuseppe Rosano, Manish M Sood, Shelley Zieroth

Erratum issuedOpen access · hybridAbstract readConsensus Statement
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of heart failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Observational
  5. Observational
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  11. Hyperkalaemia-related reduction of RAASi treatment associates with more subsequent inpatient care.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Management of hyperkalemia: Expert consensus from Kuwait - a Modified Delphi Approach.International journal of nephrology and renovascular disease · 2024
    Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 8 institutions in 5 countries.

James O BurtonDepartment of Cardiovascular Sciences, University of Leicester, Leicester, UK.ORCID 0000-0003-1176-7592
Andrew J S CoatsMonash University, Australia and the University of Warwick, Warwick, UK.
Csaba P KovesdyUniversity of Tennessee Health Science Center, Memphis, TN, USA.
Biff F PalmerUniversity of Texas Southwestern Medical Center, Dallas, TX, USA.
Ileana L PiñaCentral Michigan University, Mount Pleasant, MI, USA.
Giuseppe RosanoIRCCS San Raffaele Roma, Rome, Italy.
Manish M SoodOttawa Hospital Research Institute, University of Ottawa, Ottawa, Ontario, Canada.
Shelley ZierothUniversity of Manitoba, Winnipeg, Manitoba, Canada.
Central Michigan University · USIRCCS Ospedale San Raffaele · ITThe University of Texas Southwestern Medical Center · USUniversity of Leicester · GBUniversity of Manitoba · CAUniversity of Ottawa · CAUniversity of Tennessee Health Science Center · USUniversity of Warwick · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsRenin-angiotensin-aldosterone system inhibitors (RAASi) are guideline-recommended therapy for individuals with cardiorenal disease. They are associated with increased risk of hyperkalaemia, a common and life-threatening disorder for this population. RAASi-induced hyperkalaemia often leads to dose reduction or discontinuation, reducing cardiorenal protection. Guideline recommendations differ between specialties for the clinical management of hyperkalaemia. Using a modified Delphi method, we developed consensus recommendations for optimal management of hyperkalaemia in adults with cardiorenal disease. METHODS AND

resultsAn international steering group of cardiologists and nephrologists developed 39 statements regarding hyperkalaemia care, including risk factors and risk stratification, prevention, correction, and cross-specialty coordination. Consensus was determined by agreement on an online questionnaire administered to cardiorenal specialists across Europe and North America. The threshold for consensus agreement was established a priori by the steering group at 67%. Across November 2021, 520 responses were received from Canada (n = 50), France (n = 50), Germany (n = 54), Italy (n = 58), Spain (n = 57), the UK (n = 49), and the US (n = 202); 268 from cardiologists and 252 from nephrologists. Twenty-nine statements attained very high agreement (≥90%) and 10 attained high agreement (≥67%-<90%), with strong alignment between cardiologists and nephrologists.

conclusionA high degree of consensus regarding hyperkalaemia evaluation and management exists among healthcare professionals. Based on high levels of agreement, the steering group derived six key recommendations for hyperkalaemia prevention and management in people with cardiorenal disease. Future studies examining the quality of hyperkalaemia care delivery are required.

Indexed as

Heart FailureHyperkalemiaDelphi TechniqueHumansRenin-Angiotensin SystemCardiorenal patientsConsensus recommendationDelphi methodHyperkalaemiaNovel potassium binderRenin-angiotensin-aldosterone system inhibitors

Identifiers

PMID35791065
PMCPMC9804940
OpenAlexW4283824390

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.