ArticleMolecular plant pathology2022
Actin-bundling protein fimbrin regulates pathogenicity via organizing F-actin dynamics during appressorium development in Colletotrichum gloeosporioides.
Article in Molecular plant pathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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9 citing papers in PubMed, 28 citations in OpenAlex.
- The complex subunit VdAP-2α regulates polar growth, ergosterol metabolism, and virulence inVirulence · 2026Article
- The Histone Acetyltransferase CgHat1 Regulates Growth, Development, and Pathogenicity ofJournal of fungi (Basel, Switzerland) · 2025Article
- Article
- A three-way transcriptomic crosstalk interaction in a biocontrol agent (Bacillus velezensis), a fungal pathogen (Colletotrichum gloeosporioides), and a walnut host (Juglans regia L.).BMC plant biology · 2025Article
- Septin-dependent invasive growth by the rice blast fungusJournal of plant diseases and protection : scientific journal of the German Phytomedical Society (DPG) · 2024Article
- Advances in understanding the mechanism of resistance to anthracnose and induced defence response in tea plants.Molecular plant pathology · 2023Review
- Appressoria-Small but Incredibly Powerful Structures in Plant-Pathogen Interactions.International journal of molecular sciences · 2023Review
- Actin-bundling protein fimbrin regulates pathogenicity via organizing F-actin dynamics during appressorium development in Colletotrichum gloeosporioides.Molecular plant pathology · 2022Article
- The emerging role of septins in fungal pathogenesis.Cytoskeleton (Hoboken, N.J.)Review
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
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Abstract
Anthracnose caused by Colletotrichum gloeosporioides leads to serious economic loss to rubber tree yield and other tropical crops. The appressorium, a specialized dome-shaped infection structure, plays a crucial role in the pathogenesis of C. gloeosporioides. However, the mechanism of how actin cytoskeleton dynamics regulate appressorium formation and penetration remains poorly defined in C. gloeosporioides. In this study, an actin cross-linking protein fimbrin homologue (CgFim1) was identified in C. gloeosporioides, and the knockout of CgFim1 led to impairment in vegetative growth, conidiation, and pathogenicity. We then investigated the roles of CgFim1 in the dynamic organization of the actin cytoskeleton. We observed that actin patches and cables localized at the apical and subapical regions of the hyphal tip, and showed a disc-to-ring dynamic around the pore during appressorium development. CgFim1 showed a similar distribution pattern to the actin cytoskeleton. Moreover, knockout of CgFim1 affected the polarity of the actin cytoskeleton in the hyphal tip and disrupted the actin dynamics and ring structure formation in the appressorium, which prevented polar growth and appressorium development. The CgFim1 mutant also interfered with the septin structure formation. This caused defects in pore wall overlay formation, pore contraction, and the extension of the penetration peg. These results reveal the mechanism by which CgFim1 regulates the growth and pathogenicity of C. gloeosporioides by organizing the actin cytoskeleton.
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