ArticleActa neurologica Scandinavica2022
Fatigue 7 years post-stroke: Predictors and correlated features.
Article in Acta neurologica Scandinavica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 4 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Effectiveness of cognitive behavioral therapy in improving symptoms of fatigue in patients with stroke and multiple sclerosis: a systematic review and meta-analysis.BMC psychology · 2025Pooled it
- Prevalence, Trajectory, and Factors Associated With Patient-Reported Nonmotor Outcomes After Stroke: A Systematic Review and Meta-Analysis.JAMA network open · 2025Pooled it
- Relationships of post-stroke fatigue with mobility, recovery, performance, and participation-related outcomes: a systematic review and meta-analysis.Frontiers in neurology · 2024Pooled it
- Association of post-stroke fatigue with physical activity and physical fitness: A systematic review and meta-analysis.International journal of stroke : official journal of the International Stroke Society · 2023Pooled it
- Prevalence and biopsychosocial predictors of post-stroke fatigue in patients with minor strokes.Journal of rehabilitation medicine · 2026Observational
- The critical role of the basal ganglia in post-stroke fatigue: A pilot study.Neuroimage. Reports · 2026Article
- Nursing strategies for severe poststroke fatigue: a case report of a structured, multidimensional intervention program.Frontiers in rehabilitation sciences · 2026Article
- An investigation of post-stroke fatigue levels and influencing factors in young and middle-aged stroke patients: a cross-sectional study.Scientific reports · 2025Article
- Profiling 92 circulating neurobiological proteins identifies novel candidate biomarkers of long-term cognitive outcome after ischemic stroke.Scientific reports · 2025Article
- Post-stroke fatigue - a multidimensional problem or a cluster of disorders? A case for phenotyping post-stroke fatigue.The Journal of physiology · 2025Review
- Factors associated with post-stroke fatigue among stroke survivors: a cross-sectional study.PeerJ · 2025Article
- [Analysis of the Mediating Effect of Fatigue Between Social Support and Depression in Hospitalized Patients With Ischemic Stroke].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024Article
- Prevalence and Predictive factors of Post-Stroke Depression in Patients with Acute Cerebral Infarction.Alpha psychiatry · 2024Article
- Factors associated with fatigue among people who have returned to work after stroke: an exploratory study.Journal of rehabilitation medicine · 2024Article
- Fatigue in stroke survivors: a 5-year follow-up of the Fall study of Gothenburg.Journal of neurology · 2023Article
- Unraveling the interplay between daily life fatigue and physical activity after subarachnoid hemorrhage: an ecological momentary assessment and accelerometry study.Journal of neuroengineering and rehabilitation · 2023Observational
- Article
- Is Cardiorespiratory Fitness Independently Associated with Fatigue in Patients with Transient Ischemic Attack or Minor Stroke?Brain sciences · 2023Article
- The impact of post-stroke fatigue on work and other everyday life activities for the working age population - a registry-based cohort study.Annals of medicine · 2023Article
- Fatigue 7 years post-stroke: Predictors and correlated features.Acta neurologica Scandinavica · 2022Article
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9 authors.
Funding
Abstract
backgroundPost-stroke fatigue (PSF) is common with great impact on quality of life. We explored predictive and cross-sectionally correlated features in the long term after ischemic stroke.
methodsThis study comprises 430 participants of the prospective Sahlgrenska Academy Study on Ischemic Stroke (SAHLSIS), aged 18-69 years at index stroke. Information on acute stroke severity and cardiovascular risk factors was collected at index stroke. After 7 years, PSF was assessed by the Daily Fatigue Impact Scale (D-FIS). Cognitive, neurological, and functional outcomes, and symptoms of depression and anxiety, pain, insomnia, and physical activity were also assessed. Associations between baseline variables and PSF were analyzed by ordinal regression. Correlations between PSF and cross-sectionally assessed variables, and between PSF and baseline variables, were analyzed with Spearman's or point-biserial correlation for the whole sample and in sex-stratified analyses.
resultsAt 7 years post-stroke, 80% of the participants reported some impact of fatigue. Female sex and stroke severity were independently associated with PSF, whereas no associations were detected with baseline cardiovascular risk factors. In cross-sectional analyses at 7 years, we found correlations between PSF and poor functional, neurological, and cognitive outcomes, as well as depressive symptoms, anxiety, insomnia, pain, and low physical activity (p < .001 throughout). The correlation with insomnia was stronger in women than in men (two-way ANOVA interaction test, p = .03).
conclusionsOur findings confirm that PSF is common in the long term after ischemic stroke and show a complex interplay with sex and several other outcomes. Future studies should address causal relationships and interventions towards fatigue and coexisting features.
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