ArticleCritical care (London, England)2022
Paradoxical response to chest wall loading predicts a favorable mechanical response to reduction in tidal volume or PEEP.
Article in Critical care (London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 12 citations in OpenAlex.
- The "mechanical paradox" unveiled: a physiological study.Critical care (London, England) · 2025Trial
- Bedside detection of end-tidal overdistention: an exploratory comparison of loading maneuvers.Intensive care medicine experimental · 2026Article
- Real-time stress and strain monitoring at the bedside: new frontiers in mechanical ventilation.Frontiers in medicine · 2025Review
- Detecting end-tidal hyperinflation.Intensive care medicine · 2024Article
- The Respiratory Mechanics of COVID-19 Acute Respiratory Distress Syndrome-Lessons Learned?Journal of clinical medicine · 2024Review
- Optimized ventilation power to avoid VILI.Journal of intensive care · 2023Review
- Practical assessment of risk of VILI from ventilating power: a conceptual model.Critical care (London, England) · 2023Review
- Editorial: Lung monitoring in respiratory failure.Frontiers in medicine · 2023Article
- Chest wall loading in the ICU: pushes, weights, and positions.Annals of intensive care · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChest wall loading has been shown to paradoxically improve respiratory system compliance (C
methodsProspective, multi-center physiologic study of seventeen patients with moderate to severe ARDS who demonstrated paradoxical responses to chest wall loading. All patients received mechanical ventilation in volume control mode and were passively ventilated. Airway pressures were measured before and after decreasing/increasing V
resultsDecreasing either V
conclusionPatients with a paradoxical response to chest wall loading demonstrate uniform improvement in both DP and C
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.