ArticleBMC geriatrics2022
Research on the frailty status and adverse outcomes of elderly patients with multimorbidity.
Article in BMC geriatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Impact of Frailty on Activities of Daily Living in Hospitalized Older Adults: A Systematic Review and Meta-Analysis.Geriatrics & gerontology international · 2026Pooled it
- Frailty-Driven Prediction of Inpatient Obstructive Sleep Apnea and Related Sleep Disorder Diagnoses Using Explainable AI.Biomedicines · 2026Article
- Oral Frailty and Social Frailty Among Older Japanese.Gerodontology · 2026Article
- Effectiveness of an mHealth Exercise Program on Fall Incidence, Fall Risk, and Fear of Falling in Nursing Home Residents: The Cluster Randomized Controlled BeSt Age Trial.Sports (Basel, Switzerland) · 2026Article
- Association between frailty status and delayed observation-room retention after painless gastrointestinal endoscopy in older patients.Frontiers in medicine · 2026Article
- Risk factors and a predictive nomogram for in-hospital deep vein thrombosis in elderly patients with multiple chronic conditions.American journal of translational research · 2026Article
- NYHA classification and quality of life in older heart failure inpatients: the mediation effects of social frailty and physical frailty.BMC public health · 2025Article
- Approaches to characterising multimorbidity in older people accessing hospital care: a scoping review.European geriatric medicine · 2025Article
- Frailty in older adults: A systematic review of risk factors and early intervention pathways.Intractable & rare diseases research · 2025Review
- Abdominal obesity and frailty progression in population across different Cardiovascular-Kidney-Metabolic syndrome stages: a nationwide longitudinal study.Diabetology & metabolic syndrome · 2025Article
- Association between frailty status and health literacy in the elderly.African health sciences · 2025Article
- Determinants and risk prediction models for frailty among community-living older adults in eastern China.Frontiers in public health · 2025Article
- The impact of frailty on quality of life among older adults in nursing homes: the mediating role of psychological resilience.Frontiers in public health · 2025Article
- The association between multimorbidity patterns and physical frailty among middle-aged and older community-dwelling adults: the mediating role of depressive symptoms.Frontiers in public health · 2025Article
- The Mediating Role of Activities of Daily Living in the Relationship Between Depressive Symptoms and Multidimensional Frailty in the Elderly with Multimorbidity.Clinical interventions in aging · 2025Article
- Development and validation of a model to predict the risk of frailty in older adults with panvascular disease.Frontiers in public health · 2025Article
- Predicting Multiple Outcomes Associated with Frailty based on Imbalanced Multi-label Classification.Journal of healthcare informatics research · 2024Article
- Frailty as a breakthrough point for multimorbidity management among older adults: challenges and opportunities in China.BMJ (Clinical research ed.) · 2024Article
- Follistatin-respiratory connection predicting all-cause mortality among community-dwelling middle-to-old age individuals: Results from the I-Lan Longitudinal Study.The journal of nutrition, health & aging · 2024Article
- Association between modified frailty index and postoperative delirium in patients after cardiac surgery: A cohort study of 2080 older adults.CNS neuroscience & therapeutics · 2024Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAs patients age, the frailty of those with multimorbidity increases, often resulting in adverse health outcomes. The current study investigated the frailty status and the factors which influence it in elderly patients with multimorbidity in Chinese hospitals. The relationship between the frailty of patients with multimorbidity and adverse outcomes was explored.
methodsThe current prospective cohort study investigated inpatients in the internal medicine department of 5 tertiary hospitals in Sichuan Province, China. A total of 3836 elderly patients with multimorbidity were enrolled. Frailty was assessed using the FRAIL scale and adverse outcome events occurring during hospitalization were tracked. Descriptive statistics and logistic regressions were used for data analysis.
resultsThe prevalence of frailty was 27.2% and of pre-frailty, 58.9%. Logistic regression analysis showed that increasing age, low BMI, low education level, lack of exercise, multiple types of medications and multiple numbers of chronic diseases were the main risk factors for frailty in elderly patients with multimorbidity (OR values: 1.020, 1.469, 2.350, 2.836, 1.156 and 1.308, respectively). The incidence of adverse outcomes was 13.9% among the cohort with the most common being deep vein thrombosis (42.4%), followed by pressure injury (38.8%). Regression analysis showed a significant correlation of frailty with adverse outcome (OR: 1.496; p < 0.01).
conclusionsThe prevalence of frailty and pre-frailty in hospitalized elderly patients with multimorbidity was high. Increasing age, low BMI, low education level, lack of exercise, multiple types of medications and multiple numbers of chronic diseases were factors which influenced frailty and frailty was an important factor in the occurrence of adverse outcomes. The most common adverse outcome of elderly multimorbidity patients during hospitalization was deep vein thrombosis.
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