Evidence map›Paper›PMID 35790677›Full record

ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2022

Machine Learning-Based Analysis in the Management of Iatrogenic Bile Duct Injury During Cholecystectomy: a Nationwide Multicenter Study.

Victor Lopez-Lopez, Javier Maupoey, Rafael López-Andujar, Emilio Ramos, Kristel Mils, Pedro Antonio Martinez, Andres Valdivieso, Marina Garcés-Albir, Luis Sabater, Luis Díez Valladares and 26 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Long-term outcomes and quality of life after surgical repair of benign biliary stricture following bile duct injury during cholecystectomy.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

36 authors.

Victor Lopez-LopezDepartment of Surgery and Transplantation, Virgen de La Arrixaca Clinic and University Hospital, Murcian Institute of Biosanitary Research (IMIB), Ctra. Madrid-Cartagena, 30120, s/nEl Palmar, Murcia, Spain. victorrelopez@gmail.com.ORCID 0000-0003-1718-3352
Javier MaupoeyDepartment of Hepatobiliary Surgery and Transplants, Hospital Universitario La Fe, Valencia, Spain.
Rafael López-AndujarDepartment of Hepatobiliary Surgery and Transplants, Hospital Universitario La Fe, Valencia, Spain.
Emilio RamosDepartment of Hepatobiliary Surgery and Liver Transplant Unit, Hospital Universitari Bellvitge, University of Barcelona, Barcelona, Spain.
Kristel MilsDepartment of Hepatobiliary Surgery and Liver Transplant Unit, Hospital Universitari Bellvitge, University of Barcelona, Barcelona, Spain.
Pedro Antonio MartinezDepartment of Information and Communication Engineering, Universidad de Murcia, Murcia, Spain.
Andres ValdiviesoHepatobiliary Surgery and Liver Transplant Unit, Cruces University Hospital, Bilbao, Spain.
Marina Garcés-AlbirDepartment of Surgery, Hospital Clínico, University of Valencia, Biomedical Research Institute INCLIVA, Valencia, Spain.
Luis SabaterDepartment of Surgery, Hospital Clínico, University of Valencia, Biomedical Research Institute INCLIVA, Valencia, Spain.
Luis Díez ValladaresDepartment of Surgery, Hepatopancreatobiliary Unit, Hospital Clínico San Carlos, Madrid, Spain.
Sergio Annese PérezDepartment of Surgery, Morales University Hospital, Madrid, Spain.
Benito FloresDepartment of Surgery, Morales University Hospital, Madrid, Spain.
Roberto BrusadinDepartment of Surgery and Transplantation, Virgen de La Arrixaca Clinic and University Hospital, Murcian Institute of Biosanitary Research (IMIB), Ctra. Madrid-Cartagena, 30120, s/nEl Palmar, Murcia, Spain.
Asunción López ConesaDepartment of Surgery and Transplantation, Virgen de La Arrixaca Clinic and University Hospital, Murcian Institute of Biosanitary Research (IMIB), Ctra. Madrid-Cartagena, 30120, s/nEl Palmar, Murcia, Spain.
Valentin CayuelaDepartment of Surgery and Transplantation, Virgen de La Arrixaca Clinic and University Hospital, Murcian Institute of Biosanitary Research (IMIB), Ctra. Madrid-Cartagena, 30120, s/nEl Palmar, Murcia, Spain.
Sagrario Martinez CortijoDepartment of Surgery, Alcorcon University Hospital, Madrid, Spain.
Sandra PaternaDepartment of Surgery, Miguel Servet University Hospital, Saragossa, Spain.
Alejando SerrabloDepartment of Surgery, Miguel Servet University Hospital, Saragossa, Spain.
Santiago Sánchez-CabúsHepatobiliopancreatic Surgery Unit, Hospital de La Santa Creu I Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.
Antonio González GilDepartment of Surgery, Los Arcos del Mar Menor University Hospital, Murcia, Spain.
Jose Antonio González MasíaDepartment of Surgery, General University Hospital, Albacete, Spain.
Carmelo LoinazDepartment of General Surgery, Digestive Tract and Abdominal Organ Transplantation, Hospital Universitario, 12 de Octubre, Madrid, Spain.
Jose Luis LucenaDepartment of Surgery, Puerta del Hierro University Hospital, Madrid, Spain.
Patricia PastorDepartment of Surgery, Reina Sofía University Hospital, Murcia, Spain.
Cristina Garcia-ZamoraDepartment of Surgery, Rafael Mendez Hospital, Murcia, Spain.
Alicia CaleroDepartment of General Surgery, Elche University Hospital, University Miguel Hernández of Elche, Alicante, Spain.
Juan ValienteDepartment of General Surgery, Hellin Hospital, Albacete, Spain.
Antonio MinguillonDepartment of General Surgery, Obispo Polanco Hospital, Teruel, Spain.
Fernando RotellarHPB and Liver Transplant Unit, Department of General Surgery, Clinica Universidad de Navarra, Universidad de Navarra, Pamplona, Spain.
Jose Manuel RamiaHPB Surgery and Liver Transplantation, Dr. Balmis General University Hospital, and Alicante Institute for Health and Biomedical Research (ISABIAL), Alicante, Spain.
Cándido AlcazarHPB Surgery and Liver Transplantation, Dr. Balmis General University Hospital, and Alicante Institute for Health and Biomedical Research (ISABIAL), Alicante, Spain.
Javier AguiloDepartment of General Surgery, Hospital Lluís Alcanyís Hospital, Xàtiva, Valencia, Spain.
Jose CutillasDepartment of General Surgery, Hospital Francesc de Borja, Gandía, Valencia, Spain.
Christoph KuemmerliDepartment of Surgery and Transplantation, University Hospital Zurich, Zurich, Switzerland.
Jose A Ruiperez-ValienteDepartment of Information and Communication Engineering, Universidad de Murcia, Murcia, Spain.
Ricardo Robles-CamposDepartment of Surgery and Transplantation, Virgen de La Arrixaca Clinic and University Hospital, Murcian Institute of Biosanitary Research (IMIB), Ctra. Madrid-Cartagena, 30120, s/nEl Palmar, Murcia, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIatrogenic bile duct injury (IBDI) is a challenging surgical complication. IBDI management can be guided by artificial intelligence models. Our study identified the factors associated with successful initial repair of IBDI and predicted the success of definitive repair based on patient risk levels.

methodsThis is a retrospective multi-institution cohort of patients with IBDI after cholecystectomy conducted between 1990 and 2020. We implemented a decision tree analysis to determine the factors that contribute to successful initial repair and developed a risk-scoring model based on the Comprehensive Complication Index.

resultsWe analyzed 748 patients across 22 hospitals. Our decision tree model was 82.8% accurate in predicting the success of the initial repair. Non-type E (p < 0.01), treatment in specialized centers (p < 0.01), and surgical repair (p < 0.001) were associated with better prognosis. The risk-scoring model was 82.3% (79.0-85.3%, 95% confidence interval [CI]) and 71.7% (63.8-78.7%, 95% CI) accurate in predicting success in the development and validation cohorts, respectively. Surgical repair, successful initial repair, and repair between 2 and 6 weeks were associated with better outcomes. DISCUSSION: Machine learning algorithms for IBDI are a novel tool may help to improve the decision-making process and guide management of these patients.

Indexed as

Abdominal InjuriesBile Duct DiseasesCholecystectomy, LaparoscopicArtificial IntelligenceBile DuctsCholecystectomyHumansIatrogenic DiseaseIntraoperative ComplicationsMachine LearningRetrospective StudiesArtificial neural networkCholecystectomyIatrogenic bile duct injuryMachine learning

Identifiers

PMID35790677
PMCPMC9439981

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.