Evidence map›Paper›PMID 35790476›Full record

ArticleJournal of medical virology2022

Viral load of SARS-CoV-2 Omicron is not high despite its high infectivity.

Sonoka Yuasa, Jun Nakajima, Yuna Takatsuki, Yuta Takahashi, Chihiro Tani-Sassa, Yumi Iwasaki, Katsutoshi Nagano, Kazunari Sonobe, Tomoyo Yoshimoto, Yoko Nukui and 6 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of medical virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 28 citations in OpenAlex.

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  13. Omicron Subvariants: Clinical, Laboratory, and Cell Culture Characterization.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
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  20. Omicron Subvariants: Clinical, Laboratory, and Cell Culture Characterization.medRxiv : the preprint server for health sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Sonoka YuasaClinical Laboratory, Tokyo Medical and Dental University (TMDU) Hospital, Tokyo, Japan.
Jun NakajimaClinical Laboratory, Tokyo Medical and Dental University (TMDU) Hospital, Tokyo, Japan.
Yuna TakatsukiClinical Laboratory, Tokyo Medical and Dental University (TMDU) Hospital, Tokyo, Japan.
Yuta TakahashiClinical Laboratory, Tokyo Medical and Dental University (TMDU) Hospital, Tokyo, Japan.
Chihiro Tani-SassaClinical Laboratory, Tokyo Medical and Dental University (TMDU) Hospital, Tokyo, Japan.
Yumi IwasakiClinical Laboratory, Tokyo Medical and Dental University (TMDU) Hospital, Tokyo, Japan.
Katsutoshi NaganoClinical Laboratory, Tokyo Medical and Dental University (TMDU) Hospital, Tokyo, Japan.
Kazunari SonobeClinical Laboratory, Tokyo Medical and Dental University (TMDU) Hospital, Tokyo, Japan.
Tomoyo YoshimotoClinical Laboratory, Tokyo Medical and Dental University (TMDU) Hospital, Tokyo, Japan.
Yoko NukuiInfection Control and Prevention, Tokyo Medical and Dental University (TMDU) Hospital, Tokyo, Japan.
Hiroaki TakeuchiDepartment of Molecular Virology, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.ORCID 0000-0002-5689-9858
Kousuke TanimotoGenome Laboratory, Medical Research Institute, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.
Yukie TanakaDepartment of Molecular Microbiology, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.
Akinori KimuraInstitute of Research, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.
Naoya IchimuraClinical Laboratory, Tokyo Medical and Dental University (TMDU) Hospital, Tokyo, Japan.
Shuji TohdaClinical Laboratory, Tokyo Medical and Dental University (TMDU) Hospital, Tokyo, Japan.ORCID 0000-0002-2642-5459
Tokyo Medical and Dental University Hospital · JPTokyo Medical and Dental University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients infected with the Omicron variant of severe acute respiratory syndrome coronavirus 2 has increased worldwide since the beginning of 2022 and the variant has spread more rapidly than the Delta variant, which spread in the summer of 2021. It is important to clarify the cause of the strong transmissibility of the Omicron variant to control its spread. In 694 patients with coronavirus disease 2019, the copy numbers of virus in nasopharyngeal swab-soaked samples and the viral genotypes were examined using quantitative polymerase chain reaction (PCR) and PCR-based melting curve analysis, respectively. Whole-genome sequencing was also performed to verify the viral genotyping data. There was no significant difference (p = 0.052) in the copy numbers between the Delta variant cases (median 1.5 × 10

Indexed as

COVID-19SARS-CoV-2HumansViral LoadCOVID-19Delta variantmelting curve analysisOmicron variantSARS-CoV-2viral load

Identifiers

PMID35790476
PMCPMC9349670
OpenAlexW4283830132

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.