ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2022
[Berberine inhibits erastin-induced ferroptosis of mouse hippocampal neuronal cells possibly by activating the Nrf2-HO-1/GPX4 pathway].
Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Article
- Soy Isoflavone Supplementation in Sow Diet Enhances Antioxidant Status and Promotes Intestinal Health of Newborn Piglets.Animals : an open access journal from MDPI · 2025Article
- Pharmacological mechanisms and therapeutic prospects of plant metabolites from traditional Chinese medicine in regulating programmed cell death in Alzheimer's disease.Frontiers in pharmacology · 2025Review
- Comprehensive Analysis ofNutrients · 2024Article
- [Dexmedetomidine inhibits ferroptosis of human renal tubular epithelial cells by activating the Nrf2/HO-1/GPX4 pathway].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024Article
- [Resveratrol protects dopaminergic neurons in a mouse model of Parkinson's disease by regulating the gut-brain axisNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024Article
- Therapeutic effects of natural compounds against diabetic complications via targeted modulation of ferroptosis.Frontiers in pharmacology · 2024Review
- Sodium pyruvate exerts protective effects against cigarette smoke extract-induced ferroptosis in alveolar and bronchial epithelial cells through the GPX4/Nrf2 axis.Journal of inflammation (London, England) · 2023Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo explore the mechanism by which berberine inhibits ferroptosis of mouse hippocampal neuronal cells (HT22).
methodsCultured HT22 cells were pretreated with 30 or 60 μmol/L berberine for 2 h before exposure to 0.5 μmol/L erastin for 8 h, and the cell proliferation, intracellular ferric iron level, changes in intracellular reactive oxygen species (ROS) and cell apoptosis were detected using CCK-8, Fe
resultsTreatment with 0.5 μmol/L erastin significantly lowered the viability of HT22 cells (
conclusionBerberine can inhibit erastin-induced ferroptosis in HT22 cells possibly by activating the Nrf2-HO-1/ GPX4 pathway.
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