Evidence map›Paper›PMID 35790318›Full record

Observational studyOpen heart2022

Predictors of post-TAVI conduction abnormalities in patients with bicuspid aortic valves.

Giulia Esposito, Niraj Kumar, Francesca Pugliese, Max Sayers, Anthony Wc Chow, Simon Kennon, Mick Ozkor, Anthony Mathur, Andreas Baumbach, Guy Lloyd and 4 more

Open access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Open heart, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Giulia Esposito *King's College London Faculty of Life Sciences and Medicine, London, UK.ORCID 0000-0001-5387-0147
Niraj Kumar *Cardiology, Barts Health NHS Trust, London, UK.
Francesca PuglieseCardiology, Barts Health NHS Trust, London, UK.
Max SayersCardiology, Barts Health NHS Trust, London, UK.
Anthony Wc ChowCardiology, Barts Health NHS Trust, London, UK.
Simon KennonCardiology, Barts Health NHS Trust, London, UK.
Mick OzkorCardiology, Barts Health NHS Trust, London, UK.
Anthony MathurBarts Health NHS Trust, London, UK.
Andreas BaumbachCentre for Cardiovascular Medicine and Devices, Queen Mary University William Harvey Research Institute, London, UK.
Guy LloydCardiology, Barts Health NHS Trust, London, UK.
Aigerim MullenUniversity College London Institute of Cardiovascular Science, London, UK.
Andrew CookUniversity College London Institute of Cardiovascular Science, London, UK.
Michael MullenCardiology, Barts Health NHS Trust, London, UK.ORCID 0000-0002-4911-3511
Kush P PatelCardiology, Barts Health NHS Trust, London, UK kush.p.patel04@gmail.com.
Barts Health NHS Trust · GBUniversity College London · GBKing's College London · GB

Funding

British Heart Foundation FS/19/48/34523
6 · The paper itself

Abstract

objectivesThis study evaluates predictors of conduction abnormalities (CA) following transcatheter aortic valve implantation (TAVI) in patients with bicuspid aortic valves (BAV).

backgroundTAVI is associated with CA that commonly necessitate a permanent pacemaker. Predictors of CA are well established among patients with tricuspid aortic valves but not in those with BAV.

methodsThis is a single-centre, retrospective, observational study of patients with BAV treated with TAVI. Pre-TAVI ECG and CT scans and procedural characteristics were evaluated in 58 patients with BAV. CA were defined as a composite of high-degree atrioventricular block, new left bundle branch block with a QRS >150 ms or PR >240 ms and right bundle branch block with new PR prolongation or change in axis. Predictors of CA were identified using regression analysis and optimum cut-off values determined using area under the receiver operating characteristic curve analysis.

resultsCA occurred in 35% of patients. Bioprosthesis implantation depth, the difference between membranous septum (MS) length and implantation depth (

conclusionsIn BAV patients undergoing TAVI, short

Indexed as

Bicuspid Aortic Valve DiseaseCalcinosisTranscatheter Aortic Valve ReplacementBundle-Branch BlockHumansRetrospective StudiesAortic Valve StenosisCongenital AbnormalitiesPacemaker, ArtificialTranscatheter Aortic Valve Replacement

Identifiers

PMID35790318
PMCPMC9258482
OpenAlexW4283832430

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.