Evidence map›Paper›PMID 35789850›Full record

ArticleiScience2022

Local Drd1-neurons input to subgroups of arcuate AgRP/NPY-neurons.

Sean R Chadwick, Ali D Güler

Open access · goldAbstract read
In one paragraph

Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sean R ChadwickProgram in Fundamental Neuroscience and the Department of Biology, University of Virginia, Charlottesville, VA 22904, USA.
Ali D GülerProgram in Fundamental Neuroscience and the Department of Biology, University of Virginia, Charlottesville, VA 22904, USA.
University of Virginia · US

Funding

Interplay between circadian and reward pathways in homeostatic response and pathologyR35GM140854 · NIGMS · UNIVERSITY OF VIRGINIA · PI Ali Guler · 2021 to 2026
$3.0M
Regulation of central circadian rhythms by dopamineR01GM121937 · NIGMS · UNIVERSITY OF VIRGINIA · PI GULER, ALI · 2016 to 2020
$2.3M
Zeiss 780 NLO High Sensitivity Multiphoton Microscopy SystemS10OD016446 · OD · UNIVERSITY OF VIRGINIA · PI PERIASAMY, AMMASI · 2013 to 2013
$600k
NIGMS NIH HHS R01 GM121937NIGMS NIH HHS R35 GM140854NIH HHS S10 OD016446
6 · The paper itself

Abstract

Obesity is a pandemic afflicting more than 300 million people worldwide, driven by consumption of calorically dense and highly rewarding foods. Dopamine (DA) signaling has been implicated in neural responses to highly palatable nutrients, but the exact mechanisms through which DA modulates homeostatic feeding circuits remains unknown. A subpopulation of arcuate (ARC) agouti-related peptide (AgRP)/neuropeptide Y (NPY) (ARC

Indexed as

Cellular neuroscienceMolecular neuroscience

Identifiers

PMID35789850
PMCPMC9250019
OpenAlexW4282915146

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.