Evidence map›Paper›PMID 35789692›Full record

ArticleLancet regional health. Americas2022

Spatial clusters, social determinants of health and risk of COVID-19 mortality in Brazilian children and adolescents: A nationwide population-based ecological study.

Victor Santana Santos, Thayane Santos Siqueira, Ana I Cubas Atienzar, Maria Augusta Ricardo da Rocha Santos, Sarah Cristina Fontes Vieira, Aline de Siqueira Alves Lopes, José Rodrigo Santos Silva, Paulo Ricardo Martins-Filho, Luis Eduardo Cuevas, Ricardo Queiroz Gurgel

Open access · goldAbstract read
In one paragraph

Article in Lancet regional health. Americas, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Mapping the spatial and temporal frequency of systemic lupus erythematosus in Brazil.Revista brasileira de epidemiologia = Brazilian journal of epidemiology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. COVID-19 severe acute respiratory syndrome in Brazilian newborns in 2020-2021.Revista brasileira de epidemiologia = Brazilian journal of epidemiology · 2023
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Victor Santana SantosDepartment of Medicine, Federal University of Sergipe, Lagarto, Brazil.
Thayane Santos SiqueiraHealth Sciences Graduate Program, Federal University of Sergipe, Aracaju, Brazil.
Ana I Cubas AtienzarDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Maria Augusta Ricardo da Rocha SantosDepartment of Nursing, Federal University of Alagoas, Arapiraca, Brazil.
Sarah Cristina Fontes VieiraHealth Sciences Graduate Program, Federal University of Sergipe, Aracaju, Brazil.
Aline de Siqueira Alves LopesDepartment of Medicine, Federal University of Sergipe, Lagarto, Brazil.
José Rodrigo Santos SilvaDepartment of Statistics and Actuarial Sciences, Federal University of Sergipe, Aracaju, Brazil.
Paulo Ricardo Martins-FilhoHealth Sciences Graduate Program, Federal University of Sergipe, Aracaju, Brazil.
Luis Eduardo CuevasDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Ricardo Queiroz GurgelHealth Sciences Graduate Program, Federal University of Sergipe, Aracaju, Brazil.
Universidade Federal de Sergipe · BRLiverpool School of Tropical Medicine · GBUniversidade Federal de Alagoas · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Data regarding the geographical distribution of cases and risk factors for COVID-19 death in children and adolescents are scarce. We describe the spatial distribution of COVID-19 cases and deaths in paediatric population and their association with social determinants of health in Brazil. Methods: This is a population-based ecological study with a spatial analysis of all cases and deaths due to COVID-19 in Brazil among children and adolescents aged 0-19 years from March 2020 to October 2021. The units of analysis were the 5570 municipalities. Data on COVID-19 cases and deaths, social vulnerability, health inequities, and health system capacity were obtained from publicly available databases. Municipalities were stratified from low to very high COVID-19 incidence and mortality using K-means clustering procedures, and spatial clusters and relative risks were estimated using spatial statistics with Poisson probability models. The relationship between COVID-19 estimates and social determinants of health was explored by using multivariate Beta regression techniques. Findings: A total of 33,991 COVID-19 cases and 2424 deaths among children and adolescents aged 0-19 years were recorded from March 2020 to October 2021. There was a spatial dependence for the crude mortality coefficient per 100,000 population in the paediatric population aged 0-19 years (I Moran 0·10; Interpretation: The main clusters of risk for mortality among children and adolescents were identified in municipalities in the North and Northeast regions, which are the regions with the worst socioeconomic indicators and greatest health disparities in the country. Our findings confirmed the higher burden of COVID-19 for Brazilian paediatric population in municipalities with higher social inequality and vulnerability and worse socioeconomic indicators. To reduce the burden of COVID-19 on children, mass immunisation is necessary. Funding: None.

Indexed as

AdolescentsBrazilChildrenCOVID-19MortalitySocial determinants of healthSpatial distribution

Identifiers

PMID35789692
PMCPMC9242540
OpenAlexW4283826893

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.