Evidence map›Paper›PMID 35789442›Full record

ArticleAntonie van Leeuwenhoek2022

Global regulatory factor VeA upregulates the production of antitumor substances in endophytic Fusarium solani.

Lu Cai, Jiankang Wang, Yongjie Li, Min Qin, Xuemin Yin, Zhangjiang He, Jichuan Kang

Abstract read
PubMed Publisher
In one paragraph

Article in Antonie van Leeuwenhoek, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Biosynthesis Regulation of Secondary Metabolite Production inJournal of fungi (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Lu CaiCollege of Pharmacy, Guizhou University, Guiyang, Guizhou, People's Republic of China.
Jiankang WangSouthwest Biomedical Resources of the Ministry of Education, Guizhou University, Guiyang, Guizhou, People's Republic of China.
Yongjie LiSouthwest Biomedical Resources of the Ministry of Education, Guizhou University, Guiyang, Guizhou, People's Republic of China.
Min QinCollege of Pharmacy, Guizhou University, Guiyang, Guizhou, People's Republic of China.
Xuemin YinCollege of Pharmacy, Guizhou University, Guiyang, Guizhou, People's Republic of China.
Zhangjiang HeCollege of Pharmacy, Guizhou University, Guiyang, Guizhou, People's Republic of China. zjhe3@gzu.edu.cn.ORCID http://orcid.org/0000-0002-7120-1227
Jichuan KangCollege of Pharmacy, Guizhou University, Guiyang, Guizhou, People's Republic of China. jckang@gzu.edu.cn.
Guizhou University · CN

Funding

National Natural Science Foundation of China 31901947National Natural Science Foundation of China 32160667National Natural Science Foundation of China 32170019
6 · The paper itself

Abstract

A number of studies have demonstrated that endophytic fungi have the potential to produce antitumor active substances with novel structures and significant activities. In our previous studies, we isolated a Fusarium strain from the stem of the medicinal plant Nothapodytes pittosporoides (Oliv.). In this study, we identified this strain as Fusarium solani and found that its crude extract has significant antitumor activity against human alveolar adenocarcinoma cells (A549). We overexpressed the global regulatory factor VeA in F. solani (VeA

Indexed as

FusariumPlants, MedicinalFungiHumansAntitumor activityEndophytic Fusarium solaniGlobal regulatory factor VeAMetabolomicsTranscriptomics

Identifiers

PMID35789442
OpenAlexW4283818248

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.