Evidence map›Paper›PMID 35789072›Full record

SynthesisCancer medicine2023

Marital status and survival in cancer patients: A systematic review and meta-analysis.

Kaja Krajc, Špela Miroševič, Jakob Sajovic, Zalika Klemenc Ketiš, David Spiegel, Gorazd Drevenšek, Martina Drevenšek

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Cancer medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed, 3 pooled it
9.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 3 syntheses or guidelines pooled it, 112 citations in OpenAlex.

  1. Pooled it
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  5. Article
  6. Depressive symptoms and perceived stress in patients with head and neck cancer undergoing intensity-modulated radiation therapy: A longitudinal study.European journal of oncology nursing : the official journal of European Oncology Nursing Society · 2026
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  9. The effect of gender role stress on psychological distress in women with breast cancer after mastectomy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Kaja KrajcFaculty of Mathematics, Natural Sciences and Information Technologies, University of Primorska, Koper, Slovenia.
Špela MiroševičDepartment of Family Medicine, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.ORCID 0000-0001-5004-0607
Jakob SajovicDepartment of Stomatology, University Medical Centre Ljubljana, Ljubljana, Slovenia.ORCID 0000-0003-1633-5983
Zalika Klemenc KetišDepartment of Family Medicine, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.ORCID 0000-0002-0270-1754
David SpiegelDepartment of Psychiatry and Behavioural Sciences, Stanford University School of Medicine, Stanford, California, USA.ORCID 0000-0002-9476-9173
Gorazd DrevenšekInstitute of Pharmacology and Experimental Toxicology, Faculty of Medicine Ljubljana, University of Ljubljana, Ljubljana, Slovenia.ORCID 0000-0002-9254-4931
Martina DrevenšekDepartment of Stomatology, University Medical Centre Ljubljana, Ljubljana, Slovenia.ORCID 0000-0003-3366-5706
University of Ljubljana · SILjubljana University Medical Centre · SIStanford Medicine · USUniversity of Primorska · SI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn recent years, authors have repeatedly reported on the significance of social support in cancer survival. Although overall the studies appear to be convincing, little is known about which types of social support promote better survival rates, and which subgroups of cancer patients are more susceptible to the benefits of it. The aim of this study was to identify, organize, and examine studies reporting on the significance of social support in cancer survival.

methodsThe PubMed, CINAHL and EBSCO databases were searched using the keywords social support/marital status, cancer, and survival/mortality. Where possible we used a meta-analytical approach, specifically a random effect model, in order to combine the results of the hazard ratios in studies from which this information could be obtained. When interpreting clinical relevance, we used the number needed to treat (NNT).

resultsBetter survival was observed in married patients when compared to unmarried (single, never-married, divorced/separated, and widowed) in overall and cancer-specific survival. Gender group differences showed that the association was statistically significant only in cancer-specific survival when comparing divorced/separated male and female cancer patients (p < 0.001), thus confirming results from the previous meta-analysis.

conclusionsBeing unmarried is associated with significantly worse overall and cancer-specific survival. The most vulnerable group found in our study were divorced/separated men. The results of this review can motivate physicians, oncologists, and other healthcare professionals to be aware of the importance of patients' social support, especially in the identified sub-group.

Indexed as

NeoplasmsDivorceFemaleHumansMaleMarital StatusProportional Hazards ModelsSingle Personmarital statusneoplasmssocial supportsurvivalsystematic review

Identifiers

PMID35789072
PMCPMC9883406
OpenAlexW4283813971

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.