Evidence map›Paper›PMID 35789061›Full record

ArticleJournal of paediatrics and child health2022

COVID-19 pandemic and care of transfusion-dependent patients of thalassaemia: Experience from a paediatric centre in North India.

Nupur Parakh, Sangeeta Pahuja, Varinder Singh, Narender Kumar, Jagdish Chandra

Open access · greenAbstract read
In one paragraph

Article in Journal of paediatrics and child health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Nupur ParakhDivision of Pediatric Hematology, Department of Pediatrics, LHMC and Associated KSCH, New Delhi, India.ORCID 0000-0001-9817-7602
Sangeeta PahujaDepartment of Immuno-Haematology and Blood Transfusion, LHMC and Associated KSCH, New Delhi, India.
Varinder SinghDivision of Pediatric Hematology, Department of Pediatrics, LHMC and Associated KSCH, New Delhi, India.
Narender KumarDivision of Pediatric Hematology, Department of Pediatrics, LHMC and Associated KSCH, New Delhi, India.
Jagdish ChandraDivision of Pediatric Hematology, Department of Pediatrics, LHMC and Associated KSCH, New Delhi, India.
Mata Chanan Devi Hospital · INInstitute of Haematology and Blood Transfusion · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimCOVID-19 has presented an unprecedented challenge to health services and has significantly affected the management of non-Covid illnesses, like thalassemia. The present study documents the impact of Covid-associated restrictions and disruptions on working of the pediatric thalassemia day care centre (TDCC), and measures taken by TDCC and blood transfusion services to adapt to and mitigate the negative impact of Covid pandemic and associated lockdown on patient care.

methodsPre-transfusion haemoglobin and packed cell transfusion requirement were compared across three time periods, namely pre-lockdown, lockdown and post-lockdown in paediatric transfusion-dependent thalassaemia (TDT) patients. Caregivers were interviewed to document any problems faced by them.

resultsThe study involved 181 TDT patients. There was a significant reduction in mean pre-transfusion haemoglobin and red cells transfused during lockdown phase as compared to pre-lockdown phase. Regular care was interrupted in 45% of patients and 76% of patients getting blood from outside could not get leukoreduced red cells. Investigations, monitoring and continuity of iron chelation were also affected. Blood centre faced 30.5% reduction in blood supply during lockdown. TDCC and blood centre took several steps, including prolongation of service hours and staggering of transfusions to ensure maximum transfusions while ensuring social distancing.

conclusionThe COVID-19 pandemic imposed many unprecedented challenges to the routine care of thalassaemic patients; however, some of them could be dealt with by a proactive approach and micro-planning at the institution level. Other similar resource-limited settings could learn from experiences for continued quality care for chronic medical conditions during pandemic like situations.

Indexed as

COVID-19ThalassemiaBlood TransfusionChildCommunicable Disease ControlHumansIron Chelating AgentsPandemicsIron Chelating AgentsCOVID-19 pandemicmanagementthalassemiatransfusion

Identifiers

PMID35789061
PMCPMC9350329
OpenAlexW4283821586

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.