Evidence map›Paper›PMID 35789057›Full record

ArticleVeterinary and comparative oncology2022

Allogeneic peripheral blood haematopoietic stem cell transplantation for the treatment of dogs with high-grade B-cell lymphoma.

Alexandra Gareau, Toko Sekiguchi, Emma Warry, Alexandra Z Ripoll, Edmund Sullivan, Theresa Westfall, John Chretin, Lisa M Fulton, Michael Harkey, Rainer Storb and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Veterinary and comparative oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Alexandra GareauCollege of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA.
Toko SekiguchiCollege of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA.
Emma WarryCollege of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA.
Alexandra Z RipollCollege of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA.
Edmund SullivanBellingham Veterinary, Bellingham, Washington, USA.
Theresa WestfallBellingham Veterinary, Bellingham, Washington, USA.ORCID https://orcid.org/0000-0001-8749-6966
John ChretinVCA West LA, Los Angeles, California, USA.
Lisa M FultonMedVet Medical & Cancer Centers for Pets, Columbus, Ohio, USA.
Michael HarkeyFred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Rainer StorbFred Hutchinson Cancer Research Center, Seattle, Washington, USA.ORCID https://orcid.org/0000-0002-9343-4099
Steven E SuterCollege of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA.ORCID https://orcid.org/0000-0002-4972-3571
North Carolina State University · USBellingham Technical College · USFred Hutch Cancer Center · USThe Centers · USWest Los Angeles College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autologous peripheral blood haematopoietic stem cell transplantation (HCT) cures 33%-40% of dogs with high-grade B-cell lymphoma. We hypothesized, based on human allogeneic bone marrow transplantation literature, that transplanting dogs using canine donor leukocyte-matched CD34+ cells would lead to fewer relapses and increased cure rates. We retrospectively reviewed medical records of dogs diagnosed with high-grade B-cell lymphoma who received an identical allogeneic HCT. A total of 15 dogs transplanted at four facilities were identified. Five of fifteen dogs relapsed before transplant. The mean number of donor CD34+ cells/kg harvested and infused into recipient dogs was 8.0 × 10

Indexed as

Dog DiseasesHematopoietic Stem Cell TransplantationLymphoma, B-CellAnimalsDogsHumansNeoplasm Recurrence, LocalRetrospective StudiesTransplantation, Homologouscomparative oncologyhematologyoncologysmall animalstem cells

Identifiers

PMID35789057
PMCPMC9796125
OpenAlexW4283808444

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.