Evidence map›Paper›PMID 35789056›Full record

ArticleGeriatrics & gerontology international2022

Nomogram for predicting in-hospital mortality of nonagenarians with community-acquired pneumonia.

Yumin Zan, Weiwei Song, Yu Wang, Jiaofang Shao, Zhiyong Wang, Weihong Zhao, Jianqing Wu, Wei Xu

Open access · hybridAbstract read
In one paragraph

Article in Geriatrics & gerontology international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Yumin ZanKey Laboratory of Geriatrics of Jiangsu Province, Department of Geriatrics, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Weiwei SongDepartment of Respiratory Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China.
Yu WangKey Laboratory of Geriatrics of Jiangsu Province, Department of Geriatrics, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Jiaofang ShaoSchool of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing, China.
Zhiyong WangDepartment of Digestive Oncology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Weihong ZhaoKey Laboratory of Geriatrics of Jiangsu Province, Department of Geriatrics, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Jianqing WuKey Laboratory of Geriatrics of Jiangsu Province, Department of Geriatrics, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Wei XuKey Laboratory of Geriatrics of Jiangsu Province, Department of Geriatrics, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.ORCID https://orcid.org/0000-0002-5826-3730
Jiangsu Province Hospital · CNNanjing Medical University · CNNanjing University of Chinese Medicine · CNWuhan University · CN

Funding

Elderly Health Research Project of Jiangsu Provincial Health Commission LX2021002National Key R&D Program of China 2018YFC2002100National Key R&D Program of China 2018YFC2002102National Natural Science Foundation of China 81871100Scientific Research Project of Jiangsu Provincial Health Commission H2019036Scientific Research Project of Jiangsu Provincial Health Commission LGY2017071
6 · The paper itself

Abstract

aimNonagenarians with community-acquired pneumonia (CAP) have a high mortality rate; however, appropriate tools for reliable severity assessment in this population are lacking. The current study aimed to evaluate the risk factors and establish a nomogram to predict in-hospital mortality of nonagenarians with CAP.

methodsIn total, 304 patients aged ≥90 years who were admitted with CAP to Jiangsu Provincial People's Hospital and Jiangsu Provincial Hospital of Chinese Medicine between 2014 and 2020 were retrospectively analyzed. Clinical information, laboratory imaging results and pathogen detection were retrieved. Significant variables independently associated with CAP were identified by a logistic regression model, and a nomogram prediction model was constructed. The nomogram was compared with the widely used assessments: CURB-65, PSI and National Early Warning Score (NEWS) scores.

resultsUnivariate and multivariate logistic regression analyses identified gender, blood urea nitrogen, C-reactive protein-to-albumin ratio, Charlson Comorbidity Index and systemic immune inflammation index as independent factors that affect the prognosis. We created a nomogram for CAP based on these risk factors. The nomogram had a bootstrapped concordance index of 0.796 and was well-calibrated in the decision analysis curve range of 0.1-0.98. The area under the curve was 0.796 (95% CI: 0.74-0.85), significantly higher than for CURB-65, PSI and NEWS scores (P < 0.05).

conclusionsOur nomogram model can predict the outcome of hospitalized nonagenarians with CAP and guide clinicians to provide better treatment, leading to improved prognosis and reduced mortality. Geriatr Gerontol Int 2022; 22: 635-641.

Indexed as

Community-Acquired InfectionsPneumoniaAged, 80 and overHospital MortalityHumansNomogramsNonagenariansPrognosisRetrospective StudiesSeverity of Illness IndexCharlson comorbidity indexcommunity-acquired pneumonianomogramnonagenariansystemic immune inflammation index

Identifiers

PMID35789056
PMCPMC11503566
OpenAlexW4283819881

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.