Evidence map›Paper›PMID 35788941›Full record

ArticleJournal of clinical ultrasound : JCU2023

Reduced exercise capacity is associated with left ventricular systolic dysfunction in long-term survivors of allogeneic hematopoietic stem-cell transplantation.

Richard John Massey, Ole Henrik Myrdal, Phoi Phoi Diep, Marta Maria Burman, Lorentz Brinch, Lars Lysgaard Gullestad, Ellen Ruud, Svend Aakhus, Jan Otto Beitnes

Open access · hybridAbstract read
In one paragraph

Article in Journal of clinical ultrasound : JCU, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Richard John MasseyDepartment of Cardiology, Oslo University Hospital, Oslo, Norway.ORCID https://orcid.org/0000-0002-6609-0569
Ole Henrik MyrdalInstitute for Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Phoi Phoi DiepInstitute for Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Marta Maria BurmanInstitute for Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Lorentz BrinchDepartment of Hematology, Oslo University Hospital, Oslo, Norway.
Lars Lysgaard GullestadDepartment of Cardiology, Oslo University Hospital, Oslo, Norway.ORCID https://orcid.org/0000-0002-5932-6641
Ellen RuudInstitute for Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.ORCID https://orcid.org/0000-0002-6956-5005
Svend AakhusDepartment of Circulation and Imaging, Faculty of Medicine and Health Science, Norwegian University of Science and Technology, Trondheim, Norway.
Jan Otto BeitnesDepartment of Cardiology, Oslo University Hospital, Oslo, Norway.
Oslo University Hospital · NONorwegian University of Science and Technology · NO

Funding

EkstraStiftelsen Helse og Rehabilitering (Stiftelsen Dam)Kreftforeningen
6 · The paper itself

Abstract

purposeExercise intolerance is a common complication in survivors of allogeneic hematopoietic stem-cell transplantation (allo-HSCT). The aim of this study was to determine if cardiac function measured with echocardiography is associated with exercise capacity measured with cardio-pulmonary exercise tests in long-term survivors treated in their youth with allo-HSCT.

methodsThe study included 96 patients, of which 54.2% were female, aged 34.9 ± 11.6 years and 17.7 ± 9.3 years after allo-HSCT. Reduced exercise capacity was defined as <85% of predicted-peak oxygen uptake (VO

resultsVO

conclusionsLeft ventricular systolic dysfunction measured by GLS is associated with reduced exercise capacity in long-term allo-HSCT survivors.

Indexed as

Hematopoietic Stem Cell TransplantationVentricular Dysfunction, LeftAdolescentExercise ToleranceFemaleHumansMaleStroke VolumeSurvivorsVentricular Function, Leftcardio-pulmonary exercise testechocardiographyglobal longitudinal strainleft ventricular ejection fractionpeak ventilatory oxygen-uptakethree-dimensional echocardiography

Identifiers

PMID35788941
PMCPMC10084426
OpenAlexW4283806758

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.