Evidence map›Paper›PMID 35788872›Full record

ArticleAnalytical and bioanalytical chemistry2022

A highly sensitive strategy for glypican-3 detection based on aptamer/gold carbon dots/magnetic graphene oxide nanosheets as fluorescent biosensor.

Guiyin Li, Wei Chen, Danhong Mi, Bo Wang, HaiMei Li, Guangxiong Wu, Ping Ding, Jintao Liang, Zhide Zhou

Abstract read
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In one paragraph

Article in Analytical and bioanalytical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Guiyin LiSchool of Life and Environmental Sciences, Guilin University of Electronic Technology, Guilin, Guangxi, 541004, People's Republic of China.
Wei ChenSchool of Life and Environmental Sciences, Guilin University of Electronic Technology, Guilin, Guangxi, 541004, People's Republic of China.
Danhong MiSchool of Life and Environmental Sciences, Guilin University of Electronic Technology, Guilin, Guangxi, 541004, People's Republic of China.
Bo WangSchool of Life and Environmental Sciences, Guilin University of Electronic Technology, Guilin, Guangxi, 541004, People's Republic of China.
HaiMei LiSchool of Life and Environmental Sciences, Guilin University of Electronic Technology, Guilin, Guangxi, 541004, People's Republic of China.
Guangxiong WuSchool of Life and Environmental Sciences, Guilin University of Electronic Technology, Guilin, Guangxi, 541004, People's Republic of China.
Ping DingXiang Ya School of Public Health, Central South University, Changsha, Hunan, 410078, People's Republic of China. pingshui@csu.edu.cn.
Jintao LiangSchool of Life and Environmental Sciences, Guilin University of Electronic Technology, Guilin, Guangxi, 541004, People's Republic of China. dxljt@guet.edu.cn.
Zhide ZhouSchool of Life and Environmental Sciences, Guilin University of Electronic Technology, Guilin, Guangxi, 541004, People's Republic of China. zzdlgy@163.com.
Guilin University of Electronic Technology · CNCentral South University · CNGuangdong University of Petrochemical Technology · CN

Funding

National Nature Science Foundation of China 82073607National Nature Science Foundation of China Nos. 81760534Open Fund of Guangxi Key Laboratory of Bio-targeting Theranostics GXSWBX201903Open Fund of Guangxi Key Laboratory of Bio-targeting Theranostics Nos. GXSWBX201902
6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths in China. Glypican-3 (GPC3) is a specific antigen related to HCC, which is widely used in clinical detection as a reliable marker of HCC. In this paper, a highly sensitive homogeneous apatasensor was designed for GPC3 detection based on fluorescence resonance energy transfer (FRET) where the GPC3 aptamer labelled gold carbon dots (AuCDs-GPC3

Indexed as

Aptamers, NucleotideBiosensing TechniquesCarcinoma, HepatocellularGraphiteLiver NeoplasmsCarbonEarly Detection of CancerFluorescence Resonance Energy TransferGlypicansGoldHumansLimit of DetectionAptamers, NucleotideCarbonGlypicansGoldGPC3 protein, humangraphene oxideGraphiteFluorescence aptasensorFluorescence resonance energy transferGlypican-3Gold carbon dotsMagnetic graphene oxide

Identifiers

PMID35788872
OpenAlexW4283819060

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.