SynthesisPloS one2022
Systematic review on e-cigarette and its effects on weight gain and adipocytes.
Synthesis in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The impacts of e-cigarette flavours: An overview of systematic reviews.Addiction (Abingdon, England) · 2025Pooled it
- An International Systematic Review of Prevalence, Risk, and Protective Factors Associated with Young People's E-Cigarette Use.International journal of environmental research and public health · 2022Pooled it
- e-Cigarettes, Smoking Cessation, and Weight Change: Retrospective Secondary Analysis of the Evaluating the Efficacy of e-Cigarette Use for Smoking Cessation Trial.JMIR public health and surveillance · 2024Trial
- Association of Conventional and Electronic Cigarette Use with Obesity and Central Obesity Among Korean Adults: A Cross-Sectional Analysis of the 2016-2018 KNHANES (2016-2018).Medicina (Kaunas, Lithuania) · 2026Article
- The Insulin-Urothelial Axis: Evaluating Insulin Resistance as a Convergent Driver of Bladder Cancer Across Diverse Risk Factor Profiles.International journal of molecular sciences · 2026Review
- Eating behaviors and nutritional habits among young adults using electronic nicotine delivery systems in a multinational cross-sectional study.BMC public health · 2025Article
- Body Composition and Metabolic Profiles in Young Adults: A Cross-Sectional Comparison of People Who Use E-Cigarettes, People Who Smoke Cigarettes, and People Who Have Never Used Nicotine Products.Journal of clinical medicine · 2025Article
- School-based smoking prevention strategies for adolescents in a conservative LMIC context: a qualitative study from Egypt.Frontiers in public health · 2025Article
- Exploring Vaping Patterns and Weight Management-Related Concerns among Adolescents and Young Adults: A Systematic Review.Journal of clinical medicine · 2024Review
- Effects of Electronic Nicotine Delivery Systems Substitution on Body Weight Status: Protocol for a Systematic Review and Meta-Analysis.JMIR research protocols · 2024Article
- Effects of Short-term Electronic(e)-Cigarette Aerosol Exposure in the Mouse Larynx.The Laryngoscope · 2024Article
- Dual Electronic and Combustible Cigarette Use: Understanding the Relation of Cannabis Use with E-Cigarette Outcomes.Substance use & misuse · 2024Article
- Hepatic steatosis induced by nicotine plus Coca-Cola™ is prevented by nicotinamide riboside (NR).Frontiers in endocrinology · 2024Article
- Metabolic and Other Endocrine Elements with Regard to Lifestyle Choices: Focus on E-Cigarettes.Metabolites · 2023Review
- Metabolic Adverse Effects of Psychotropic Drug Therapy: A Systematic Review.European journal of investigation in health, psychology and education · 2023Review
- Article
- Environmental factors of obesity before and after COVID-19 pandemic: a review.Frontiers in public health · 2023Review
- E-cigarette exposure causes early pro-atherogenic changes in an inducible murine model of atherosclerosis.Frontiers in toxicology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Smoking and obesity are leading causes of morbidity and mortality worldwide. E-cigarette which was first introduced in 2000s is perceived as an effective alternative to conventional tobacco smoking. Limited knowledge is available regarding the risks and benefits of e-cigarettes. This study systematically reviews the current literature on the effects of e-cigarettes on body weight changes and adipocytes. The search was performed using OVID Medline and Scopus databases and studies meeting the inclusion criteria were independently assessed. This review included all English language, empirical quantitative and qualitative papers that investigated the effects of e-cigarettes on bodyweight or lipid accumulation or adipocytes. Literature searches identified 4965 references. After removing duplicates and screening for eligibility, thirteen references which involve human, in vivo and in vitro studies were reviewed and appraised. High prevalence of e-cigarette was reported in majority of the cross sectional studies conducted among respondent who are obese or overweight. More conclusive findings were identified in in vivo studies with e-cigarette causing weight decrease. However, these observations were not supported by in vitro data. Hence, the effect of e-cigarette on body weight changes warrants further investigations. Well-designed population and molecular studies are needed to further elucidate the role of e-cigarettes in obesity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.