Evidence map›Paper›PMID 35788104›Full record

ArticleeNeuro

Sex Differences in the Alcohol-Mediated Modulation of BLA Network States.

Alyssa DiLeo, Pantelis Antonoudiou, Spencer Ha, Jamie L Maguire

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Early Life Stress Impairs VTA Coordination of BLA Network and Behavioral States.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alyssa DiLeoProgram in Neuroscience, Graduate School of Biomedical Sciences, Tufts University, Boston, Massachusetts 02111.
Pantelis AntonoudiouDepartment of Neuroscience, Tufts School of Medicine, Tufts University, Boston, Massachusetts 02111.
Spencer HaDepartment of Neuroscience, Tufts School of Medicine, Tufts University, Boston, Massachusetts 02111.
Jamie L MaguireDepartment of Neuroscience, Tufts School of Medicine, Tufts University, Boston, Massachusetts 02111 jamie.maguire@tufts.edu.ORCID https://orcid.org/0000-0002-4085-8605
Tufts University · US

Funding

Neuroactive steroids as novel psychiatric treatments: mechanistic studiesP50MH122379 · NIMH · WASHINGTON UNIVERSITY · PI MAGUIRE, JAMIE LYNN · 2021 to 2025
$12.2M
Investigating the pathological consequences of seizure-induced activation of the HPA axisR01NS102937 · NINDS · TUFTS UNIVERSITY BOSTON · PI Jamie Lynn Maguire · 2017 to 2026
$4.2M
Stress-induced impairments in endogenous neurosteroid signaling in the BLA negatively impacts network and behavioral statesR01MH128235 · NIMH · TUFTS UNIVERSITY BOSTON · PI MAGUIRE, JAMIE LYNN · 2021 to 2025
$2.5M
Interneurons tune the neural circuits mediating the anxiolytic effects of alcoholR01AA026256 · NIAAA · TUFTS UNIVERSITY BOSTON · PI MAGUIRE, JAMIE LYNN · 2018 to 2022
$1.9M
Disruption in the network communication of safety in epilepsy with comorbid anxietyR01NS105628 · NINDS · TUFTS UNIVERSITY BOSTON · PI MAGUIRE, JAMIE LYNN · 2019 to 2022
$1.6M
Basolateral amygdala response to acute alcohol predicts voluntary drinkingF31AA028410 · NIAAA · TUFTS UNIVERSITY BOSTON · PI DILEO, ALYSSA · 2021 to 2022
$63k
NIAAA NIH HHS F31 AA028410NIAAA NIH HHS R01 AA026256NIMH NIH HHS P50 MH122379NIMH NIH HHS R01 MH128235NINDS NIH HHS R01 NS102937NINDS NIH HHS R01 NS105628
6 · The paper itself

Abstract

Alcohol use, reported by 85% of adults in the United States, is highly comorbid with mood disorders, like generalized anxiety disorder and major depression. The basolateral amygdala (BLA) is an area of the brain that is heavily implicated in both mood disorders and alcohol use disorder. Importantly, the modulation of BLA network/oscillatory states via parvalbumin (PV)-positive GABAergic interneurons has been shown to control the behavioral expression of fear and anxiety. Further, PV interneurons express a high density of δ subunit-containing GABA

Indexed as

AlcoholismBasolateral Nuclear ComplexAnimalsEthanolFemalegamma-Aminobutyric AcidInterneuronsMaleMiceMice, Inbred C57BLParvalbuminsSex CharacteristicsEthanolgamma-Aminobutyric AcidParvalbuminsalcoholbasolateral amygdalaGABAnetwork statesoscillationssex differences

Identifiers

PMID35788104
PMCPMC9275151
OpenAlexW4283801422

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.